hodgkin lymphoma Flashcards
1
Q
lymphomas are malignancy of
A
lymphocytes
2
Q
lymphomas often involve
A
lymph nodes
3
Q
signs of lymphomas
A
enlarged painless LN
4
Q
defining characteristic of Hodgkin lymphoma
A
reed sternberg cells
5
Q
reed sternberg cell characteristics
A
multi lobed, derived from B cells
6
Q
reed sternberg markers
A
CD15+, CD30+
7
Q
reed Sternberg cells release
A
cytokines generating reactive cells
8
Q
reed Sternberg cells can activate macrophages causing
A
hypercalcemia (b/c macrophages release 1 alpha hydroxylate)
9
Q
hodgkin lymphoma commonly presents as
A
cervical lymphadenopathy
10
Q
nodule lymphocyte predominant variant malignant cells
A
LP cells (variant of reed Sternberg)
11
Q
surface marker for nodule lymphocyte predominant variant
A
CD20 (lack CD15 & CD30)
12
Q
nodular sclerosing variant often presents as
A
mediastinal mass
