blood groups

Question 1

patients who lack A or B generate

Answer 1

antibodies

Question 2

A, B antibodies are what type

Answer 2

IgM

Question 3

Rh system are all

Answer 3

transmembrane proteins

Question 4

D antigen is

Answer 4

highly immunogenic

Question 5

Rh negative may develop

Answer 5

anti-D antibodies

Question 6

anti-D antibodies are what type of antibodies

Answer 6

IgG

Question 7

what type of antibodies can cross the placenta

Answer 7

IgG

Question 8

newborn hemolytic disease is classically caused by

Answer 8

anti-D (anti-Rh) antibodies

Question 9

newborn hemolytic disease can only occur in

Answer 9

D- mother with D+ baby

Question 10

newborn hemolytic disease sxs

Answer 10

hydrops fetalis (massive edema)

Question 11

newborn hemolytic disease prevention

Answer 11

anti-D globulin (RhoGAM) which are IgG antibodies to D antigen is given to mother and macrophages rapidly clear D+ RBCs

Question 12

blood type testing

Answer 12

patient RBCs plus antibodies and look for agglutination

Question 13

type and screen

Answer 13

recipient serum plus standard RBCs to screen for patient antibodies to rare antigens

Question 14

packed RBCs is

Answer 14

RBC with plasma removed

Question 15

packed RBCs minimizes

Answer 15

vol given to patient

Question 16

platelets express

Answer 16

ABO and HLA class I antigens

Question 17

fresh frozen plasma corrects def in

Answer 17

clotting factors

Question 18

cryoprecipitate is precipitate that forms when

Answer 18

fresh frozen plasma is thawed

Question 19

cryoprecipitate contain lots of

Answer 19

fibrinogen

Question 20

acute hemolytic transfusion reaction

Answer 20

preformed antibodies to donor RBCs

Question 21

acute hemolytic transfusion reaction is what type of hypersensitivity reaction

Answer 21

type II

Question 22

acute hemolytic transfusion reaction is usually from

Answer 22

incorrect blood product

Question 23

sxs of acute hemolytic transfusion reaction

Answer 23

fever, chills, flank pain, jaundice, dark urine

Question 24

anaphylaxis is a

Answer 24

allergic type I sensitivity reaction

Question 25

anaphylaxis sxs

Answer 25

hives, angioedema, wheezing, and hypotension

Question 26

anaphylaxis may occur in

Answer 26

IgA def individuals

Question 27

febrile non-hemolytic transfusion reaction sxs

Answer 27

fever, chills, and no other systemic sxs

Question 28

febrile non-hemolytic transfusion reaction caused by

Answer 28

cytokines in blood products esp IL-1

Question 29

transfusion related acute lung injury results from

Answer 29

neutrophil activation