sexual dysfunction Flashcards
what drug can cause sexual dysfunction
SSRI SNRI
in that case can be swithced to bupropion
cause of ED
HPT or CV
neuropathy caused by diabetes
depression stress
HPT drugs
drugs that can cause ED
alcohol
SSRIs SNRIs
BB clonidine thiazides
1st gen antipsych such as chlorpromazine
prolactin raising 2nd gen such as risperidone, paliperidone
BPH meds- finasteride, dutasteride
non drug tx for ED
weight loss
smoke cessation
alcohol reduction
natural meds for ED
yohimbe
L arginine
ginsing (risk of bleeding)
drug tx for ED
PDE-5 inhibitors
alprostadil
BPH meds
tadalafil at 5mg
PAH tx
Sildenafil revatio and
tadalafil Adcirca
PDE5 inhibitors MOA
blocks PDE5 from degrading cGMP (cgmp causes relaxation of smooth muscles)
PDE5 inhibtors for ED
sildenafil viagra
vardenafil levitra
tadalafil cialis
avanafil stendra
what should PDE5 inhibitros not used with
nitrates or riociguat
AE of PDE5
hearing loss
visionloss
hypotenstion
priapsim >4 hours erection
no more than 1 dose per day
**CYP3A4 inhibitors be careful
dose for PDE5is
V 50mg starting
L C 10mg
Stendra 100mg
when to reduce dose and by how much
if >65
using Alpha blocker
CYP3A4i
renal or liver disease
reduce dose by 50%
alprostadil MOA
prostaglandin E1 moa- vasodilator allows blood to flow into the arteries
injected to the penis
