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naplex > pharmakogenomics > Flashcards

pharmakogenomics Flashcards

1
Q

HLA

A

human leukocyte antrigen

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2
Q

HLA resting for

A

abacavir
allopurinol
carbamazepine
oxcarbamazepine
phenytoin
fosphenytoin

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3
Q

cyp2c19

A

clopid

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4
Q

cyp2d6

A

codiene

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5
Q

warfarin

A

cyp2c9 and VKORk

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6
Q

her2 gene negetive do not use

A

trastuzumab (herceptin)

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7
Q

KRAS positive do not use

A

cetuximab (erbitux)

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8
Q

TMPT is low start a low dose

A

azathioprine

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9
Q

DPD defeciency do not use

A

caepcitabine
fluorouracil

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10
Q

positive HLA indicates

A

risk of hypersensitivity

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11
Q

positive KRAS mutation

A

poor response to drug

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12
Q

HER 2 negative

A

avoid drug

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naplex (78 decks)

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