acute coronary syndromes Flashcards
risk factors for ACS
same as SIHD
what is the dose for SL nitrate for angina or ACS
one every 5 mins upto 3
what is the difference between SIHD and ACS
ACS is NSTEMI STEMI and UA
how to differentiate ACS
cardiac enzyme positive for STEMI and NSTEMI
ECG- STEMI shows ST elevation
blockage is complete in ST
treatment for STEMI and NSTEMI
STEMI- MONA GAP BA +PCI/CABG/fibrinolytics
NSTEMI- MONA GAP BA +- PCI
BOTH- antiplatelets, anti anginal, anticoag
MONA - morphine, Oxygen, nitrates, aspirin
GAP- GPII antagonists, anticoags, P2Y12
BA- BB, acei
what are the first choice for ACS
MONA
- O2 if <90 sat
- SL 0.4 nitates, contraindicated with PD5
What are 2nd choice for ACS
GAP
-abciximab(repro), eptifibatide(integrillin), tirofiban(aggrastat)
- LMWH, UF, bivalirudin( pref for STEMI)
- Clopid, prasu(prodrugs) tica is not a prodrug
what are continued outpatient for ACS
BB adn ACE
what is a fibrinolytic
Alteplase (Activase)
tenecteplase (TNKASE)
MOA binding to fibrin and converting plasminogen to plasmin
ONLY FOR STEMI
used within 30 mins of hospitalization
what is the only P2Y12 inhibitor
cangrelor kegreal
loading dose of ticagrelor
180 mg with ASA 325
maintanence dose of ticagrelor
09mg bid and then 60mg bid after 1 year with ASA<100
secondary prophylaxis for ACS
ASA
P2Y12
nitro SL
BB
ACE
aldosterone antagonist
statin
STEMI drug associated with lowering mortalilty
nifedipine immediate release
AE of brillinta
dyspnea, bleeding increase in sc
