ID:2 Flashcards
pre op abx timing
cephazolin / cefuroxime 60 mins (clinda if beta lactam allergy)
vanc/quinolones 120 mins
during op
if >3-4 hours or major blood loss
additional dose
post opp
abx not required or d/c by 24 hours
colo rectal sx what abx should be used
cefotetan/cefoxitin unasyn ertapenem
metronidazole +ceftriaxone
if beta lactam allergy then use clinda+aminoglycoside
metro + amino glycoside
meningitis
> 1 month to 50 years ceftriaxone +vanco
50 amp+ceftriax+vanc
<1 month amp+cefotaxime or getna
*ceftriaxone for neo nates is a no no
acute otitis media
tylenol
observe for 2-3days temp<102
amoxicillin or 1st 2nd 3rd gen cephalosporin
bronchitis
abx for 5-7days
augmentin
azithromycin
doxycycline
if dypsnea increase, sputum inncrease, mechanical ventilation
abx not recommended unless pertussis or pneumonia
hospital acquired pneumonia
> 48 hours after hospital admin
risk for MRSA is IV use of abx in the last 90 days
also >10% in hospital
also nasal swab test
ventilator associated pneumonia
> 48 hours after ventilation admin
tx of HAP and VAP
p. areugenisa
- zosyn/ cefepime
MRSA
- vanc or linezolid
use 2 for p.aruginosa
- MDR risk - cipro/ genta
- do not use 2 beta lactams together
latent TB tx
isoniazid and rifapentine for 12 weeks
rifampin for 4 months
isoniazid +rifampin for 3 months
** alternate tx
Isoniazid for 6 months or 9 months- pref in gregnancy
active TB tx
RIPE for 2 months
rifampin
isoniazid
pyrazinamide
ethambutol
extended tx will include RI
rifampin AE
orange red discolaration of body fluids
increase LFTs
hemolytic anemia
flu like symptoms
isoniazid AE
peripheral neuropathy- use B6 pyroxidine to halt these AE
hepatitis
DILE
pyrazinamide AE
acute gout
increase LFTs
ethambutol
increase LFTs
optic neuritis
confusion
hallucinations
DDI of rifampin
PI
warfarin
contraceptives
Tx resistant to ripe
use quinolones
do not use Pyrazinamide in gout
infective endo carditis tx
IV abx for 4-6 weeks
vanc mono
naf + genta
ntal prophylaxis
amoxcillin
alt
amp/cefazolin
clinda azithro
SBP
ceftriaxone 5-7 days \
alt
ampi/genta/quinolone
SBP prophylaxis
bactrim cipro
cholecystitis
metronidazole
4-7 dayse
7-14 days
>14 days
peritonitis cholangitis mild
cefoxitin
ertapenem
moxifloxa