schizophrenia Flashcards
what NT affected in schiczo
dopamine
serotonin
glutamine
negative signs for schz
- harder to treat
loss of interest
lack of emotions
poor hyegine
social withdrawal
loss of motivation
lack of speech
positive signs of schz
hallucinations
delusions
disorganized thinking /behavior
natural mded
fish oil
rugs
second gen antipsych are 1st line lower EPS
what are EPS
dystonia
akathasia
parkinsonism
tardive dyskensiais
what drugs can cause psychotic syndromes
anticholinergics
dextromethorphen
dopamine agonist
interferons
stimulants
steroid
which two meds shouldnt be given together causes sedation
olanzapine and benzos
BW for antipscyh
agitation
psychosis
morality CV risk stroke
warnings - hyperprolacteminemia
NMS
EPS
1st gen
moa- blocking dopa 2 recentpro and minimal serotonisn blocker
low potency is more sedation but less EPS
low potency 1st gen
chlorpromazine
thiridazone
mid potency 1st gen
loxapine
perphenazine
high potency 1st gen
haloperidol haldol
fluphenazine
thiothixene
trifluoperazine
2nd gen
blocks dopa 2 and serotonin receptors
aripriprazole
clozapine
lurasidone
olanzapine
paliperidone
quetiapine
risperidone
ziprasidone
brexipiprazole
cardiac risk qt risk drugs
ziprasidone
haloperidol
thiorizadone
chlorpromazine
history of parkinsons
avoid high risk drugs EPS causing 1st gen
also
risperidone and paliperidone
overweight do not use
olanzapine or quetiapine
non adherent ?
use long acting IM
quick antipscyh
haloperidol cocktail
ziprasidone IM
olanzapine IM
chronic treatment
long acting IM injections or
ODTs- abilifym olanzapine risperidone
SL- asenapine
liquids- aripriprazole fluphenazine
haloperidol risperidone
patch-asenapine
failiure with tx use
clozapine tabs
