cystic fibrosis Flashcards
CF is
an incurable heredetery disease from mutation in the gene for cystic fibrosis transmembrane conductance regulator- abnormal secretion of chloride, bicarb and sodium affects lungs pancrease liver and intestines
symptoms of CF
sallty tasting skin, poor growth adn poor weight gain
steatorrhea
tx
lung complications treated with local methods- inhalations
order is important
chronic lung infection treated 28 days on and 28 days off - azithromycin indirectly
order of tx
inhaled bronchodilators(albuterol)–>
hypertonic saline (hypersal)–>
Dornase Alfa (pulmozyme) –>
chest physiotherapy —>
inhaled abx
what airway clearance therapies are used
brochodilators
hypertonic saline
dornase alfa
ornase alfa
ampules stored in the refrigerator
protect from light
do not mix with any other drug
abx inhaled for psudomonas
tobramycin (TOBI)
aztreonam
oral azithromycin
what abx in Cystic can cause otoxicity
tobramycin
which medication is 28days on 28days off
azetreonam
pancrelipase contains
lipase protease amylase
Creon
pan-CRE-lipase
zenpep
contains pancreatic enzyme product PEP
ViokACE
ase-ace
only tablet and should be used with PPI
AE of pancrelipase
abdominal pain, flatulence nausea
notes on Pancrelipase
do not refrigerate
dispense in original container
protect from moisture
do not crush or chew the tabs only DR can be mixed with soft food
