migraine Flashcards
cause
imbalance of oneurotransmitter
menstrual
wtih aura
foods- alcohol, beer, redwine, cheese , chocolate, aspartame, caffeine
stress
snsory
wake sleep pattern
barometric pressure
diagnosis
HA lasting 4-72 hours
unilateral, pulsating, moderate -severe pain
N/V/photophobia
non drug tx
TENS
natrual products
caffiene
butterbur
feverfew
mg
riboflavin
co q10
peppermint
drug tx
triptans or serotonin receptor agonist
calcitonin gene related peptide CGRP
opiods
triptans
5HTP receptor causign vasoconstriction of cranial blood vessels
almotriptan
eletriptan (relpax)
frovatriptan (Frova)
Naratriptan (Amerge)
Rizatriptan (maxalt)
sumatriptan (Iitrex, onzetra tosymra)
Zolmitriptan (Zomig
what are some contraindication for triptans
CV
HPT
IHD,
do not use within 24 hours of another triptan
SSRis
warnings with triptans
increase in BP serotonin syndrome
which triptan can be used by >6 year old
rizatriptan
which triptan has the longest halflife
frovitriptan, onset is slower
whihc triptans are ODT
rizatriptan and zolmitriptan
which triptan is nasl spray
suma and zolmi
which triptan is powder
sumatriptan
which triptan is sc
suma
ergotamine drugs
non selective agonist of serotonin receptor
dihydroergotamine
ergotamine plus caffiene
do not use with CYP3A4 inhibitors
other durgs
rimegepant (nurtec ODT)
ubrogepant (ubrelvy)
which is a controlled med used for migrane
lasmiditan (reyvow)- selective 5HT1F receptor
fioronal
butalbital
barbituate
fiorocet- ACE/BUT/CAF with cod
Fiorinal- ASA/BUT/CAF with cod
prophylactic tx of migrane
> 2 days weekly or >3 times monthly
BB (propranolol timolol and metoprolol
topiramate and valporic acid (teratogenic)
TCA- amitriptyline venlafaxine
ergotamine AE
CV effects do not use in pregnant patients
which triptans are contraindicated with MAO
suma , riza zolmi
age restrictions for triptans
riza>6
zoli >12
almo>12
treximat >12
not suma
what med is good for menses related migraine
sasoniq birth control
migranol
dihydroergotamine
