GERD

Question 1

drugs that can worsen GERD

Answer 1

NSAIDS/ ASA
bisphos
dabigatran
estrogen
fish oil
iron supplements
nicotine
steroids
tetracyclines

Question 2

life style mods

Answer 2

weight loss
head elevation
avoid high fat before sleep
avoid caffine , acidic, spicy ,carbonated food

Question 3

drug tx

Answer 3

PPI for 8 weeks can increase to BID if nocturnal sx

Question 4

maintenence

Answer 4

PPI low dose
H2Ra
metochlopramide or sucralfate

Question 5

antacids

Answer 5

Calcium carbonate
MG OH
sodium bicarb

Question 6

aluminum and MG can cause

Answer 6

accumulation and renal dysfunction

Question 7

aluminum

Answer 7

constipation, hypo phosphatemia

Question 8

MG

Answer 8

diarrhea *use with aluminum helps

Question 9

Calcium

Answer 9

causes constipation but pref in pregnancu

Question 10

H2 RA

Answer 10

famotidine
ranitidine
cimetidine

Question 11

pepcid

Answer 11

famotidine

Question 12

zantac

Answer 12

ranitidine *removed from market

Question 13

H2Ras can cause

Answer 13

confusion > 50 years of age
cimetidine- gynecomastia , impotence

Question 14

PPIs

Answer 14

esomeprazole
lansoprazole
omeprazole
dexlansoprazole
pantoprazole

Question 15

which PPis recommended before breakfast

Answer 15

nexium
prevacid
prilosec

Question 16

which PPis dont need meals

Answer 16

Panto
dexlanso

Question 17

what are some AE of PPIs

Answer 17

C diff
hypo mg
Vit B12 defeciency
osteoporis for long term use
avoid with clopid

Question 18

which PPis are available in IV

Answer 18

panto and esomeprazole

Question 19

metoclopramide moa

Answer 19

dopamine antagonist
higher doses blocks serotonin receptors which help with nausea and vomiting
Increases LES tone and gastric emptying `

indicated for gastroparesis

Question 20

AE of metochlopramide

Answer 20

avoid in parkinson
can cause tardive dyskinesia
drowsiness diarrhea

Question 21

drug interactions with ANTACID PPI AND H2RAs

Answer 21

antiretrovirals
antivirals
azole
iron
cephalosporin
mesalamine
risendronate

Question 22

PEPTIC ULVER DISEASE

Answer 22

H pylori
NSAID induced
stress ulcer induced

Question 23

diagnostic tests

Answer 23

UBT urea breath test

Question 24

drug tx

Answer 24

quadruple therapy
triple therapy f clarithromycin resistance rates are low

Question 25

quad therpay 10-14 days

Answer 25

bismuth 300mg QID
metronidazole 250-500mg QID
tetracycline 500mg QID
PPI BID
pylera +PPI

Question 26

another quad therapy

Answer 26

amox 1000mg BID
clarithro 500mg BID
metro 250mg QID
PPI BID

Question 27

triple therapy

Answer 27

amox 1000mg BID
clarithro 500mg BID
PPI BID

or Prevpac (amox+clarithro+lanso)

Question 28

moa of sucralfate

Answer 28

physcial barrier

Question 29

misoprostol moa

Answer 29

prostaglandin E1 analog

Question 30

Hpylori looks like

Answer 30

gram - spiral shaped

Question 31

med not indicated in preg or <8 years

Answer 31

tetra cycline

Question 32

which 2 ppi DDI with clopid

Answer 32

omeprazole and esomeprazole

Question 33

which PPi comes in ODT

Answer 33

lansoprazole Prevacid

Question 34

which PPI doesnt have capsule formulation to be mixed with food

Answer 34

pantoprazole

Question 35

PPI in hospital can cause

Answer 35

pneumonia

Question 36

vimovo

Answer 36

naproxen and esomeprazole

Question 37

pylera

Answer 37

bismuth / metro/ tetra QID