GERD Flashcards
drugs that can worsen GERD
NSAIDS/ ASA
bisphos
dabigatran
estrogen
fish oil
iron supplements
nicotine
steroids
tetracyclines
life style mods
weight loss
head elevation
avoid high fat before sleep
avoid caffine , acidic, spicy ,carbonated food
drug tx
PPI for 8 weeks can increase to BID if nocturnal sx
maintenence
PPI low dose
H2Ra
metochlopramide or sucralfate
antacids
Calcium carbonate
MG OH
sodium bicarb
aluminum and MG can cause
accumulation and renal dysfunction
aluminum
constipation, hypo phosphatemia
MG
diarrhea *use with aluminum helps
Calcium
causes constipation but pref in pregnancu
H2 RA
famotidine
ranitidine
cimetidine
pepcid
famotidine
zantac
ranitidine *removed from market
H2Ras can cause
confusion > 50 years of age
cimetidine- gynecomastia , impotence
PPIs
esomeprazole
lansoprazole
omeprazole
dexlansoprazole
pantoprazole
which PPis recommended before breakfast
nexium
prevacid
prilosec
which PPis dont need meals
Panto
dexlanso
what are some AE of PPIs
C diff
hypo mg
Vit B12 defeciency
osteoporis for long term use
avoid with clopid
which PPis are available in IV
panto and esomeprazole
metoclopramide moa
dopamine antagonist
higher doses blocks serotonin receptors which help with nausea and vomiting
Increases LES tone and gastric emptying `
indicated for gastroparesis
AE of metochlopramide
avoid in parkinson
can cause tardive dyskinesia
drowsiness diarrhea
drug interactions with ANTACID PPI AND H2RAs
antiretrovirals
antivirals
azole
iron
cephalosporin
mesalamine
risendronate
PEPTIC ULVER DISEASE
H pylori
NSAID induced
stress ulcer induced
diagnostic tests
UBT urea breath test
drug tx
quadruple therapy
triple therapy f clarithromycin resistance rates are low
