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naplex > GERD > Flashcards

GERD Flashcards

1
Q

drugs that can worsen GERD

A

NSAIDS/ ASA
bisphos
dabigatran
estrogen
fish oil
iron supplements
nicotine
steroids
tetracyclines

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2
Q

life style mods

A

weight loss
head elevation
avoid high fat before sleep
avoid caffine , acidic, spicy ,carbonated food

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3
Q

drug tx

A

PPI for 8 weeks can increase to BID if nocturnal sx

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4
Q

maintenence

A

PPI low dose
H2Ra
metochlopramide or sucralfate

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5
Q

antacids

A

Calcium carbonate
MG OH
sodium bicarb

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6
Q

aluminum and MG can cause

A

accumulation and renal dysfunction

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7
Q

aluminum

A

constipation, hypo phosphatemia

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8
Q

MG

A

diarrhea *use with aluminum helps

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9
Q

Calcium

A

causes constipation but pref in pregnancu

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10
Q

H2 RA

A

famotidine
ranitidine
cimetidine

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11
Q

pepcid

A

famotidine

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12
Q

zantac

A

ranitidine *removed from market

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13
Q

H2Ras can cause

A

confusion > 50 years of age
cimetidine- gynecomastia , impotence

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14
Q

PPIs

A

esomeprazole
lansoprazole
omeprazole
dexlansoprazole
pantoprazole

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15
Q

which PPis recommended before breakfast

A

nexium
prevacid
prilosec

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16
Q

which PPis dont need meals

A

Panto
dexlanso

17
Q

what are some AE of PPIs

A

C diff
hypo mg
Vit B12 defeciency
osteoporis for long term use
avoid with clopid

18
Q

which PPis are available in IV

A

panto and esomeprazole

19
Q

metoclopramide moa

A

dopamine antagonist
higher doses blocks serotonin receptors which help with nausea and vomiting
Increases LES tone and gastric emptying `

indicated for gastroparesis

20
Q

AE of metochlopramide

A

avoid in parkinson
can cause tardive dyskinesia
drowsiness diarrhea

21
Q

drug interactions with ANTACID PPI AND H2RAs

A

antiretrovirals
antivirals
azole
iron
cephalosporin
mesalamine
risendronate

22
Q

PEPTIC ULVER DISEASE

A

H pylori
NSAID induced
stress ulcer induced

23
Q

diagnostic tests

A

UBT urea breath test

24
Q

drug tx

A

quadruple therapy
triple therapy f clarithromycin resistance rates are low

25
Q

quad therpay 10-14 days

A

bismuth 300mg QID
metronidazole 250-500mg QID
tetracycline 500mg QID
PPI BID
pylera +PPI

26
Q

another quad therapy

A

amox 1000mg BID
clarithro 500mg BID
metro 250mg QID
PPI BID

27
Q

triple therapy

A

amox 1000mg BID
clarithro 500mg BID
PPI BID

or Prevpac (amox+clarithro+lanso)

28
Q

moa of sucralfate

A

physcial barrier

29
Q

misoprostol moa

A

prostaglandin E1 analog

30
Q

Hpylori looks like

A

gram - spiral shaped

31
Q

med not indicated in preg or <8 years

A

tetra cycline

32
Q

which 2 ppi DDI with clopid

A

omeprazole and esomeprazole

33
Q

which PPi comes in ODT

A

lansoprazole Prevacid

34
Q

which PPI doesnt have capsule formulation to be mixed with food

A

pantoprazole

35
Q

PPI in hospital can cause

36
Q

vimovo

A

naproxen and esomeprazole

37
Q

pylera

A

bismuth / metro/ tetra QID

naplex (78 decks)

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