Seronegative Spondylo's - Reactive Arthritis + IBD-related arthropathy Flashcards
Reactive Arthritis (aka Reiter’s syndrome);
Acute, ? lower limb arthritis occurring 4-? days following an infection, usually ?/? (infection may have been ?).
Common pathogens are ?, ? or ?.
o Ask about ? ? for atypical organisms.
asym 40 GI/GU aSx campylobacter salmonella chlamydia foreign travel
Reactive Arthritis (aka Reiter’s syndrome);
This can then develop into a ? arthritis.
More commonly affects ? (80% HLA B27 positive)
The joints themselves are ?, with the disease process due to ? stimulation of the inflammatory response (c.f. ? joint).
chronic males sterile antigenic septic
Reactive Arthritis (aka Reiter’s syndrome);
Presentation; o Classical triad : 'can' t ?, can't ? or climb a ?' • ?itis. • ?. • ?-limb oligoarthritis.
o ?itis and ?itis may also develop in susceptible individuals
see
pee
tree
conjunctivitis
dysuria
lower
spondylitis
sacroiliitis
Reactive Arthritis (aka Reiter’s syndrome);
Presentation o ? is common. • Often associated ? ? or ?tendonitis. o ? lesions are common. --> • ? ?: plaques similar to psoriasis. • ? in the uncircumcised male.
enthesitis plantar fasciitis achilles skin keratoderma blenorrhagica balanitis
Reactive Arthritis (aka Reiter’s syndrome);
Management;
o Full dose ? +/- ? ?.
o ? is second line for more extensive disease.
nsaids
ster inj
sulfasalazine
IBD-related arthropathy;
10-?% of those with IBD develop an arthropathy.
Presentation;
o Usually a ? arthritis affecting ? limb joints.
o 5% will also have ?/? involvement.
Can ? the IBD.
15 sym lower spinal SIJ predate
IBD-related arthropathy;
Remission of ? usually leads to remission of joint disease, but arthritis persists even in well-controlled ?.
Treatment is ?-related, with discussion between the ?
and ?.
uc crohns mdt gastroenterologists rheumatologists