OA - Background

Question 1

Most common type of arthritis.
Results from a disparity between the ? applied to ? cartilage and the ability of the cartilage to withstand that ?.
Commonly affects the ?, ?, ???, ???, thumb ??? and hallux ??? joints
Commonly spares the ????’s

Answer 1

stress
articular
stress
knee
hip
DIP 
PIP
CMC
MTP
MCPJ

Question 2

Clinical Features;

? pain;
o Initial ? related pain, then finally a constant ? pain.

Stiffness;
o Characteristically ? after periods of rest (‘?’), but lasts under ? mins
-
Symptoms classically follow a ? and ? course (good/bad days).
Later features are muscle ?, loss of ?, ? and joint
?.

Answer 2

progressive
activity
rest
worse
gelling
30
waxing
waning
wasting
mobility
deformity
instability

Question 3

On examination;
o Look: bony ?, muscle ?.
o Feel: ? ? tenderness, possible ?, ?.
o Move: limited ? ? ?

OA can either be localised (e.g. classically ? or ? OA) or ? (affecting
many joints).

Answer 3

swelling
wasting
joint line
effusion
crepitus
ROM

hip
knee
generalised

Question 4

Risk Factors;

?.
?.
Family History: ? predisposition.
Gender: ? OA more common in women, particularly after
?.
Hyper?
Previous ?.
Occupation (?, ? etc.).

Protective Factors;
?

Answer 4

age
obesity
genetic
polyarticular
menopause
hypermobility
trauma
farmer
miner
osteoporosis

Question 5

Secondary OA can develop due to;

–Pre-existing ? damage: inflammatory/?/? arthritis, ???,
trauma.

–Metabolic disease: ?ly, ?sis, ?sis.

–Systemic disease: ? (leading to haemarthroses),
?ies, ?ies

Answer 5

joint
septic
crystal
AVN
acromegaly
haemochromatosis
chondrocalcinosis
haemophilia
haemoglobinopathies
neuropathies

Question 6

? OA is rarely symptomatic, unless accompanied by ?.

? radiological/pathological OA is not always symptomatic, showing the ? correlation between disability, symptoms and ? change.

Poor ? strength and ? mood are better predictors of pain
than ? severity.

Answer 6

early
advanced
poor
structural
quadriceps
depressed
radiological