Primary Tumours of Bone + Soft Tissue

Question 1

Tumours of the bone are most commonly ? metastases, or tumours of the
? ? cells (most commonly ?).

Malignant tumours of the bone itself are comparatively ?, most commonly
? or ?.

Answer 1

bloodborne
haemopoietic marrow
myeloma

rare
osteosarcoma
chondrosarcoma

Question 2

Osteosarcoma;

Malignant tumour of ?, growing ? to invade surrounding ? ? and metastasising ?, often to the ?.
Very poor prognosis (?-?% 5 year survival). occurs in ?, most commonly around the ?.
Often ? at presentation.
Rarely can occur in ? patients, associated with long-standing ?

Answer 2

osteoblasts
rapidly
soft tissue
early
lung
5-10
children
knee
advanced
elderly
pagets

Question 3

Chondrosarcoma;
-Malignant ? forming lesion, growing ? and metastasising
?.
Can be very ? at presentation, but generally stay within a ? border .
They occur in ?, most common around the ?.
Presx is with pain, ? symptoms or occasionally a ? ?

Answer 3

cartilage
slowly
late
large
defined
adults
pelvis
mechanical
pathological fracture

Question 4

Benign tumours such as ?, ?, and ? are a DDx to these malignant tumours.
Further ? and ? is always indicated to determine the nature of a lesion detected on ?

Answer 4

osteoma
chondroma
osteochondroma
imaging
biopsy
xr

Question 5

Chronic ? and ? fractures can also commonly mimic the symptoms of bone tumours, and can have variable ? findings.

Management is generally aimed at ?, with ?preservation secondary.
?-? resection with adjunctive ?/? is commonly seen.

Answer 5

osteomyelitis
stress
radiological
survival
limb
en-bloc
CTx/RTx