Paget's Disease of the Bone - Ix + Mx

Question 1

Bloods;
? raised, calcium and phosphate ?.
Can be a mild ? in widespread disease.
Urine;
Raised ? due to increased bone turnover.

Answer 1

alp
normal
hypercalcaemia
hydroxyproline
``

Question 2

XR;
Variable presentation, with ? and ? lesions.
Bone scans;
Used to show extent of bone involvement, but cannot differentiate between
?’ s and sclerotic ?.

Answer 2

lytic
sclerotic
pagets
mets

Question 3

Treatment;
? analgesics for the pain.
? for disease modification (IV or oral).
Monitor serum ? as a disease marker.

Answer 3

simple
bisph
alp

Question 4

Treatment
? patients may be treated if there are significant risk factors for
complications.
Surgery may be required to deal with ? joint disease or ?
complications.

Answer 4

aSx
secondary
neuro