respiratory: glucocorticoids

Question 1

glucocorticoids MOA

Answer 1

prevent inflammation, suppress airway mucus production, and promote responsiveness or beta 2 receptors in the bronchial tree, reduces airway mucosal edema

Question 2

glucocorticoids (corticosteroids) meds

Answer 2

• belomethasone
• budesonide
• flucticasone
• combinations inhaled meds
• prednisone (oral)

Question 3

glucocorticoids theraputic uses

Answer 3

long term prophylaxis of asthma

Question 4

glucocorticoids complications

Answer 4

• diffuculty speaking/ hoarseness (beclomethasone inhaled)
• candidiasis (beclomethasone inhaled)

prednisone (oral)

• supression of adrenal gland function
• bone loss
• hyperglycemia
• myopathy
• peptic ulcer disease
• infection
• fluid/ electrolyte imbalances

Question 5

glucocorticoids contraindications/interactions

Answer 5

contraindications

• live virus vaccine
• systemic fungal infections
• cause: diabetes, hypertension, heart failure, peptic ulcer disease, osteoporosis, kidney disfunction

interactions

• inhaled glucocorticoids: ketoconazole
• prednisone: potassium-depleting diuretics, NSAIDS, hypoglycemic agents

Question 6

glucocorticoids pt. teaching

Answer 6

• use with a space as directed
• rinse mouth after each use (1 min between puffs)
• take with food (oral form)
• avoid NSAIDS- use Tylenol instead
• increase fluid intake
• take enough calcium and vitamin D
• report s/s of adverse effects

Question 7

glucocorticoids nursing implications

Answer 7

• assess and monitor resp status
• monitor for adrenal insufficiency (anorexia, nausea, weakness, fatigue, hypotension, hypoglycemia) may be life threatening
• monitor for side effects
• do not stop abruptly; must taper down
• monitor blood sugar levels frequently
• monitor for s/s of infection
• do not use wth NSAIDS
• rinse mouth after inhaler use to avoid thrush