hemologic and immune pharmothereaputics: antiplatlets

Question 1

antiplatlets MOA

Answer 1

• prevent platelets from clumping together by inhibiting enzymes and factors that normally lead to arterial clotting
• also inhibit platlet aggregation at the onset of the clotting process, thus altering bleeding times

Question 2

antiplatlets therapeutic uses

Answer 2

prevent mis, stroke or tia, manage acute coronary syndromes and intermittent claudication

Question 3

antiplatlets common meds

Answer 3

aspirin
clopidogrel
ticagrelor

Question 4

antiplatlets complications

Answer 4

• go effects (n/v) dyspepsia
• hemorrhagic stroke
• prolonged bleeding time, gastric bleed, thrombocytopenia
• tinnitus, hearing loss (toxic levels)

Question 5

antiplatlets contraindications

Answer 5

• bleeding disroders
• thrombocytopenia
• caution with peptic ulcer disease, serve kidney or liver disorders
• aspirin- do not give to children that have viral infection (risk of reyes syndrome)

Question 6

antiplatlets interactions

Answer 6

• other meds that increase bleeding
• herbal supplement that increase bleeding
• other saids
• urine acidifiers, corticosteroids, caffeine (can increase aspirin levels)

Question 7

antiplatlets nursing implications

Answer 7

• monitor for s/s of bleeding
• monitor platelet levels
• make sure aspirin is taken with food
• don’t take aspirin with other nsaids- can cause reduced blood thinning effect
• monitor for s/s toxicity

Question 8

antiplatlets pt. teaching

Answer 8

• take with food
• monitor for s/s of bleeding and notify your provider
• don’t take with nsaids for herbal supplements that increase bleeding
• notify your doctors if you develop ringing in your ears or hearing loss