cardio: cardiac glycoside

Question 1

cardiac glycoside moa

Answer 1

positive inotropic effect; an increased force of myocardial contraction
negative chronotropic; decreased heart rate

Question 2

common cardiac gylcosdie and what is it used for

Answer 2

digoxin

used for

• 2nd line heart failure
• dysrhythmias (atrial fibrillation

Question 3

cardiac glycoside therapeutic effects

Answer 3

• heartbeats stronger and more effectively

- decreased heart rate

Question 4

cardiac glycoside onset, peak, duration, routes, antidote

Answer 4

onset: 30-120 min (po) 5-30 min (IV)
peak: 6-8 hours (Po) 1-5 hr (IV)
duration: 3-4 days (Po, IV)
routes: PO,IV
antidote: digoxin immune fab (Ovine), digibind, antigen-binding fragments

Question 5

cardaic glycoside complications

Answer 5

• dysrhythmias
• digoxin toxicity
• gi effects
• cns effects

Question 6

cardac gycoside common side effects

Answer 6

• fatigue
• bradycardia
• anorexia
• n/v

Question 7

cardiac glycoside toxicity

Answer 7

above 2

Question 8

cardiac glycoside contraindications

Answer 8

• ventricular rhythm disturbances
• a-v heart block
• cautiously with hypokalemia, partial av block, advanced heart failure, impaired kidney function

Question 9

cardiac glycoside interactions

Answer 9

• thiazide diuretics
• loop diuretics
• ace inhibitors and ARBS
• dopamine
• quinidine
• verapamil
• antacids