Psych drugs Flashcards
List the 6 typical anti-psychotics
+common suffix
Haloperidol Pimozide Trifluoperazine Fluphenazine Thioridazine Chlorpromazine (azine/azide)
(Haloed pimps & trifling thieves flew by cheating)
increase cAMp
block D2 receptor
typical anti-psychotics
High potency typical antipsychotics
Haloperidol
Trifluoperazine
Fluphenazine
(trifling Halos flew High)
Low potency typical antipsychotics
Chlorpromazine, Thioridazine
cheating theives are low
List 1 atypical antipsychotic and the other’s 2 common suffix
Aripiprazole
(+apine)(+Peridone/ idone)
asenapine, clozapine, quetipine,
iloperidone, paliperidone, risperidone, lurasidone, ziprasidone
serotonin and D2 antagonist
Atypical antipsychotic mechanisms
which atypical anti-psychotic is apartial D2 agonist
Aripiprazole
Ari is a pipsqueak and an atypical pop-star
causes agranulocytosis and seizures
Clozapine; atypical
watch clozapine closely
causes hyperprolactenemia (galactorrhea, amenorrhea, man boobs/ gynecomastia)
Risperidone; atypical
makes me think of the ice-cream a raspado. ice-cream is milky
causes metabolic syndrome
weight gain, dyslipidemia, diabetes
-apines; atypicals
causes a prolonged QT interval
less EPS and anticholinergic side effects
all atypical anti-psychotics
aripip,
apines,
per(idones)
For treatment resistant schizophrenia &
schizophrenia associated with Suicidality
Clozapine
Clozapine can cause
Metabolic syndrome
Myocarditis
Seizures
and what else
agranulocytosis
Causes sedation, anticholinergic side effects, and orthostatic hypotension
Chlorpromazine, Thioridazine
1st gen low potency
Can cause sudden onset sustained muscle contractions (Dystonia)
Haloperidol
Trifluoperazine
Fluphenazine
(typical antipsychotics high potency)
Can cause Tremor, Rigidity, Blunted affect, and Bradykinesia
Haloperidol
Trifluoperazine
Fluphenazine
(typical antipsychotics high potency)
Can cause subjective restlessness with inability to sit still (Akathisia)
Haloperidol
Trifluoperazine
Fluphenazine
(typical antipsychotics high potency)
Can cause involuntary tics or choreoathetoid movements after chronic use
Haloperidol
Trifluoperazine
Fluphenazine
(typical antipsychotics high potency)
Fever, Rigidity with Hyporeflexia, mental status change, Hypertension, tachycardia, diaphoresis
use of Dopamine Antagonist
Neuroleptic malignant syndrome
Schizophrenia: excess dopamine in this pathway
Mesolimbic
Fever, Clonus with Hyper-reflexia, mental status change, Hypertension, tachycardia, diaphoresis
use of SSRI
Serotonin Syndrome
Drug-induced parkinsonism is caused by dopamine (D2) receptor blockade in the ____ pathway.
nigrostriatal
Drug-induced parkinsonism is caused by 1st generation antipsychotics and …
Antiemetics/gastric motility agents
metoclopromide/ prochlorepezine
Mood stabilizer for
Manic & Depressive features
Lithium
Mood stabilizer for
Manic features
Valproate, Carbamazepine
Mood stabilizer for
Depressive features
Lamotrigene
Mood stabilizer with following AE: Diabetes insipidus Tremor Hypothyroidism Teratogen (Heart problems)
Lithium
Mood stabilizer with following AE:
Hepatotoxicity
Teratogen (neural tube defects)
Valproate
Mood stabilizer with following AE:
Aplastic Anemia
SIADH
Teratogen (neural tube defects)
Carbamezapine
Mood stabilizer with following AE:
Benign Rash
Steven Johnson Syndrome
Lamotrigene
