Lipoprotein functions

Question 1

Delivers dietary TGs to peripheral tissues. Delivers cholesterol to liver in the form of chylomicron remnants, which are mostly depleted of their TGs. Secreted by intestinal epithelial cells

Answer 1

Chylomicron

Question 2

Delivers hepatic TGs to peripheral tissue. Secreted by liver.

Answer 2

VLDL

Question 3

Delivers TGs and cholesterol to liver. Formed from degradation of VLDL

Answer 3

IDL

Question 4

Delivers hepatic cholesterol to peripheral tissues. Formed by hepatic lipase modification of IDL in the liver and peripheral tissue. Taken up by target cells via receptor-mediated endocytosis

Answer 4

LDL

Question 5

Mediates reverse cholesterol transport from peripheral tissues to liver. Acts as a repository for apo-lipoproteins C and E (which are needed for chylomicron and VLDL metabolism). Secreted from both liver and intestine. Alcohol synthesis

Answer 5

HDL

Question 6

________ are composed of varying proportions of cholesterol, TGs, and phospholipids. LDL and HDL carry the most cholesterol.

Cholesterol is needed to maintain cell membrane integrity and synthesize bile acids, steroids, and vitamin D

Answer 6

Lipoproteins