prelim genetics lesson 1 fundamental Flashcards
is the basic structural and functional unit of all living organisms.
Cell
It is the smallest unit of life and can replicate independently.
CELL
The study of cell is called
Cell Biology
cell vary from individual “single cell” organisms (____) to “multicellular” structures (tissues, organs) and organisms (____).
bacteria; animals and plants
Cell was discovered by __
Robert Hooke in 1665
The discovery of the cell was made possible through the invention of the microscope
1590, Hans and Zacharias Janssen
He first observed the cell in
thin slices of bottle cork.
Robert Hooke
Hooke discovered many tiny pores that he named “cells”. This came from the Latin word “__”.
Cella
He described the cells as tiny boxes or a honeycomb. He thought that cells only existed in plants and
fungi.
Robert Hooke
Robert Hooke, Drawing of the structure of cork by Robert Hooke that appeared in book “__”
Micrographia
Used a handmade microscope to observe pond scum and discovered
single-celled organisms. He called them “____”.
Anton van Leeuwenhoek (1673), animalcules
He also observed blood cells from fish, birds, frogs, dogs and humans. This is probably due to the widely accepted, traditional belief in ___
Anton van Leeuwenhoek (1673),Spontaneous Generation
In 19th century; many doubted Spontaneous Generation and this was disproved by
Louis Pasteur
German Botanist,
_____, concluded that all plant
parts are made of cells.
1838, Matthias Schleiden
German physiologist, _____ who was a close friend of
Schleiden, stated that all animal tissues are composed of cells.
1839, Theodor Schwann
German physician, after extensive study of
cellular pathology, concluded that cells must arise from preexisting cells.
1858, Rudolf Virchow
3 CLASSIC CELL THEORY
*All organisms are composed of one or more cells .
- Cell is the basic unit of life in all living things.
*All cells are produced by the division of preexisting
cells.
4 Modern Cell Theory:
- The cell contains hereditary information (DNA) which is passed on from cell to cell during cell division.
- All cells are basically the same in chemical composition and metabolic activities.
- All basic chemical and physiological functions are carried out inside the cells (movement, digestion etc) .
- Cell activity depends on the activities of sub-cellular
Basic morphologic and functional unit of all living things
cell
First step in cell reproduction:
DNA replication
Capable of independent existence (under favorable environmental conditions)
cell
Combination of cells with the same general function
tissue
Combination of tissues that form a more complex functional
ORGAN
Group of organs that have interrelated functions
ORGAN SYSTEM
Approximate number of human cells
30 trillion
MOST ABUNDANT TYPE OF CELL IN THE BODY
80% are RBCs (red blood cell)
Approximate number of neurons (actual value closer to 86 billion)
100 billion
Approximate number of glial (supporting) cells
1 trillion
PROKARYOTES (PRO- ____ , KARYON- ___)
FIRST FORMED;NUCLEUS
organism that lacks a membrane bound nucleus (karyon),
single celled
Cell division occurs mainly by
binary fission
were the first form of life on Earth.
Prokaryotic cells
They are simpler and smaller
than Eukaryotic cells.
Prokaryotic cells
multicellular organism that have specialized organelles in the cytoplasm, a membrane bound nucleus enclosing genetic material organized into chromosomes. Their cell division occurs by __ and ___.
EUKARYOTES; mitosis and meiosis
EUKARYOTES (EU-___, KARYON-___)
TRUE; NUCLEUS
These cells are larger than a typical prokaryote
EUKARYOTES
70 S ribosome is found. (subunit : 50S
and 30S)
Prokaryotic
Nucleolous present
Eukaryotic
80S ribosome is found. (subunit :
60 S and 40S)
Eukaryotic
cell wall of Peptidoglycan
Prokaryotic
Absence of Peptidoglycan
Eukaryotic
Pseudopodia absent
Prokaryotic
Pseudopodia Present in some
Eukaryotic
Made up of polysaccharide or polypeptide
CAPSULE
Evasion of phagocytosis, adherence and attachment, resistance to desiccation
CAPSULE
Gives shape and resistance to lysis by osmotic shock
CELL WALL
Made up of peptidoglycan
CELL WALL
ENDOTOXIN (Gram (-) bacteria)
CELL WALL
Maintains cell integrity; regulates transport,
specialized function (respiration, photosynthesis, protein
secretion)
CYTOPLASMIC MEMBRANE
Hair-like structures on cell
PILUS
-pilin (protein)
PILUS
bacterial mating in conjugation,
twitching motility,
PILUS
-flagellin (protein), motility, chemotaxis, run and tumble
movement (undulating)
FLAGELLUM
Viscous aqueous suspension of protein,
CYTOPLASM
- Protein synthesis
- 70s made up of 50s and 30s subunits (Svedberg)
RIBOSOMES
Nuclear area or nucleoid
GENOME
Survival during conditions of desiccation, nutrient depletion and waste build-up
SPORE
- Single DNA molecule
- Circular chromosome
GENOME