anaphy integumentary system Flashcards
which means inward
integumentare
meaning to cover
tegere
Composed of skin, hair,
glands, nails and sensory
receptors.
INTEGUMENTARY SYSTEM
The skin acts as a barrier against physical damage, UV radiation, and pathogens
PROTECTion
The skin synthesizes vitamin D when exposed to sunlight.
Vitamin D Production
The skin excretes some waste products through sweat,
Excretion
The skin contains numerous nerve endings that detect touch
Sensation
by controlling blood flow near the surface
Temperature regulation
aka_____ or
integument covers the external
surface of the body.
Skin/cutaneous membrane
in both surface area and weight
(16% of total body weight).
❑ Thickest:
❑ Thinnest:
❑ 2 parts:
Largest organ of the body
heels
eyelids
epidermis and dermis
It consists mainly of a stratified squamous keratinized
epithelium
Epidermis
Keratin synthesis
Keratinocytes
Pigment production;
PROTECTS THE DNA
Melanocytes
Antigen presenting cell (a
type of macrophage)
Langerhans cells
Tactile epithelial cells
Merkel cells
Stratum basale (basal layer) and the thicker stratum spinosum (spinous layer) are collectively called
Malpighian layer
Layers of Epidermis:
Outermost layer
Absent in thin skin
Granular layer
Thickest layer
Mitotic division
Stratum Corneum
Stratum Lucidum
Stratum Granulosum
Stratum Spinosum
Stratum Basale
germ cell where mitosis
occur / stem cells
Basal Layer/ Germinativum
Cells are arranged as a single layer of
cuboidal or low columnar cells
Keratinocyte stem cells undergo mitotic divisions approximately every
19 days
with their associated Merkel discs are scattered among the keratinocytes of the basal layer.
Melanocytes and Merkel cells
Thickest and still the thickest even in
thin skin
Stratum Spinosum
Aka Prickle cell layer/ Spinous layer
Stratum Spinosum
Composed of polyhedral keratinocytes
with active protein synthetic function
KERATIN SYNTHESIS
Connected by desmosomes
Stratum Spinosum
where langerhan cells are located
Stratum Spinosum
Organelles begin to degenerate
Stratum Granulosum/Granular Layer
Three to five rows of flattened
keratinocytes
Stratum Granulosum/Granular Layer
thin, transparent/clear zone that consists of several layers
of dead cells (3-5 layers)
Stratum Lucidum
Stratum Lucidum Present in thick skin:
fingertips, palms, and soles.