Physiology- oxygen transport in blood Flashcards

1
Q

what is cyanosis?

A

abnormal bluish discolouration of the skin and mucous membranes due to high levels of deoygenated Hb

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2
Q

patient has decreased blood flow and increased oxygen extraction. Which type of cyanosis is most likley?

a. peripheral
b. central

A

A.peripheral

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3
Q

patient has decreased Hb saturation and abnormal Hb . Which type of cyanosis is most likley?

a. peripheral
b. central

A

b.central

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4
Q

which law states : the total pressure exerted by the mixture of inert gases is equal to the sum of the partial pressures of individual gases in a volume of air

a. Henrys
b. Ficks
c. Daltons

A

c.Dalton

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5
Q

which law states : the number of molecules dissolving in a liquid is directly proportional to the partial pressure of the gas

a. Henrys
b. Ficks
c. Daltons

A

a. Henrys

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6
Q

true or false concentration of gas in a solution is equal to partial pressure

A

false

solubility of a gas affects its conc

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7
Q

which of these factors is not one of the 3 factors dictating the paO2?

a. alveolar ventilation
b. exertion
c. conc of O2 inspired
d. ventilation perfusion matching

A

b.exertion

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8
Q

the max amount of O2 that can combine with Hb is known as?

a. partial pressure
b. FiO2
c. oxygen capacity

A

c. oxygen capacity

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9
Q

what is the correct equation for oxygen saturation?

a. volume of oxygen bound to Hb/ oxygen capacity
b. volume of oxygen bound to Hb x oxygen capacity
c. oxygen capacity/ volume of oxygen bound to Hb

A

a.volume of oxygen bound to Hb/ oxygen capacity x100 for %

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10
Q

what does saO2 represent?

a. volume of oxygen in arterial blood
b. O2 saturation in arterial blood
a. volume of oxygen in alveolar blood
b. O2 saturation in alveolar blood

A

b. O2 saturation in arterial blood

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11
Q

what does a pulse oximeter measure ?

a. volume of oxygen in arterial blood
b. O2 saturation in arterial blood
a. volume of oxygen in alveolar blood
b. O2 saturation in alveolar blood

A

b. O2 saturation in arterial blood

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12
Q

what is the correct oxygen content of one L the blood?

a. 201 ml/l
b. 3ml/l
c. 204 ml/l
d. 150g/l

A

c. 204 ml/l

201 from o2 bound with Hb
3ml/l in plasma

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13
Q

how much Hb is present in the a litre of blood?

what is the correct oxygen content of one L the blood?

a. 201 ml/l
b. 3ml/l
c. 204 ml/l
d. 150g/l

A

d.150 g/l

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14
Q

For each g of Hb how much O2 can bind?

a. 1.34 g
b. 1.34 mol
c. 1.34 ml

A

c.1.34 ml

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15
Q

what is the main role of po2?

a. driving force for saturating Hb with O2
b. transferring O2 out of the blood to the tissue

A

a.driving force for saturating Hb with O2

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16
Q

Which two factors determine blood oxygen content

a. saO2 and pO2
b. SaO2 and Hb conc

c, pO2 and Hb conc

A

b. SaO2 and Hb conc

17
Q

At what point does cyanosis show?

a. more than or equal to 50g/l deoxy Hb or 33% of total Hb
b. when hypoxia begins
c. more than or equal to 50g/l deoxy Hb or 50% of total Hb

A

a. more than or equal to 50g/l deoxy Hb or 33% of total Hb

18
Q

Which of these Ox- Hb curves is furthest right ?

a. arterial
b. venous

19
Q

Which of these oxy-Hb dissociation curves has the highest pO50?

a. venous
b. arterial

20
Q

What is the role of 2,3 -DPG?

a. bind oxyhaemoglobin
b. bind deoxyhaemoglobin
c. increase oxygen saturation
d. driving force for saturating Hb with oxygen

A

b.bind deoxyhaemoglobin

21
Q

Which blood has a lower po50 on an oxy-Hb dissociation curve?

a. fetal
b. maternal

22
Q

A blood with a higher O2 affinity will be shifted in which direction?

a. right
b. down
c. up
d. left

23
Q

what happens oxygen dissociation curve for anaemia ?

a. right
b. down
c. up
d. left

24
Q

oxygen consumption = arterio - venous difference x cardiac output

is referred to by which principle ?

a. Henrys
b. Ficks
c. Daltons

A

b. ficks principle

25
which is the correct equation for oxygen consumption? a. arterio venous difference x cardiac ouput b. arterio venous difference / cardiac output c. arteral o2 + venous o2 / cardiac output
a. arterio venous difference x cardiac ouput
26
what is the average cardiac output per min ? a. 1 l/min b. 2l/min c. 3l/min d. 4l/min e. 5l/min
e.5l/min
27
what type of hypoxia is caused by low uptake of O2 at the lungs? a. hypoxic b. anaemic c. ischaemic d. histoxic
a.hypoxic
28
what type of hypoxia is caused by low haemoglobin levels? a. hypoxic b. anaemic c. ischaemic d. histoxic
b.anaemic
29
what type of hypoxia is caused by low O2 in the circulation? a. hypoxic b. anaemic c. ischaemic d. histoxic
c.ischaemic
30
what type of hypoxia is caused by low tissue utilisation of O2? a. hypoxic b. anaemic c. ischaemic d. histoxic
d.histoxic
31
high altitude and lung failure cause which type of hypoxia? a. hypoxic b. anaemic c. ischaemic d. histoxic
a.hypoxic
32
iron defficiency and CO poisoning cause which type of hypoxia? a. hypoxic b. anaemic c. ischaemic d. histoxic
b.anaemic
33
shock, heart failure and embolism cause which type of hypoxia? a. hypoxic b. anaemic c. ischaemic d. histoxic
c.ischaemic
34
cyanide poisoning (inhibiting mitochondria) cause which type of hypoxia? a. hypoxic b. anaemic c. ischaemic d. histoxic
d.histoxic