Pathology - Pathophysiology of lung diseases Flashcards
what type of ventilatory defect is asthma?
a. obstructive
b. restrictive
a.obstructive
what part of the lung is hyper responsive to allergens in asthma?
a. bronchus
b. alveolus
c. trachea
a.bronchus
what cell type is increased in asthma?
a.neutrophil
b.monocyte
c,eosinophil
d.basophil
c,eosinophil
inflammation
what type of muscle constricts in asthma?
a. skeletal
b. cardiac
c. smooth
c.smooth
what is the effect of asthma on spirometry?
a. abnormal
b. no effect
a.abnormal
what is the correct equation for % predicted spirometry?
a. actual value/ predicted value x 100
b. predicted value / actual value x 100
a.actual value/ predicted value x 100
what is true for obstructive disease spirometry?
a. FEV1 increase, FVC decrease
b. FEV1 decrease, FVC decrease to lesser extent
c. FEV1 decrease, FVC increase
b.FEV1 decrease, FVC decrease to lesser extent
what is the main cause of COPD?
a. hypertension
b. atherscelrosis
c. smoking
d. obesity
c.smoking
true or false infections exacerbate the symptoms of COPD?
a. true
b. false
a.true
coarse crepitations and wheeze heard on auscultation what does this suggest?
a. restrictive defecct
b. obstructive defect
c. COPD
c.COPD
what type of fibres are destroyed in emphysema?
a. collagen
b. fibroelastic
c. elastin
c.elastin
which of these does not cause destruction of elastin fibres?
a. smoking
b. a1 anti trypsin deficiency
c. lung infection
c. lung infection
what happens to lung compliance in emphysema?
a. increase
b. decrease
a.increase
elastic recoil less so lungs can expand further
lung compliance
expandability
what happens to airway resistance in emphysema ?
a. decrease
b. no change
c. increase
c.increase
what happens to transfer factor in emphysema?
a. decrease
b. no change
c. increase
a.decrease
true or false emphysema leads to loss of alveoli?
a. true
b. false
a.true
what happens in the spirometry of emphysema?
a. FEV1 nad FVC both decrease
b. FEV1 decreases more than FVC
c. FVC decreases more than FEV1
b.FEV1 decreases more than FVC
what happens to FEV1:FVC ratio in obstructive?
a. increased
b. reduced
c. reduced <0.7
c.reduced <0.7
which of these is not a cause of increased pulmonary vascular resistance?
a. hypoxia
b. thrombo embolism
c. stroke
d. schistosomiasis
c.stroke
what type of shunt leads to pulmonary hypertension when oxygenated blood from the heart goes back into the pulmonary veins?
a. left to right
b. right to left
a.left to right
which of these causes a V/Q mismatch?
a. asthma
b. pulmonary hypertension
c. emphysema
b.pulmonary hypertension
what does dyspnoea, syncope, cough,haemoptysis and an increased pulmonary second heart sound and right ventricular heave indicate?
a. asthma
b. pulmonary hypertension
c. emphysema
b.pulmonary hypertension
which of these is heard in pulmonary hypertension?
a. wheeze and coarse crepitations
b. right ventricular heave, increased pulmonary second heart sounds
b. right ventricular heave, increased pulmonary second heart sounds