Physiology - leucocytes and plasma proteins Flashcards
which of these is not a function of white blood cells?
a. carrying O2
b. immune response
c. inflammatory response
d. disposal of damaged and aging cells
a.carrying O2
what is the cfirst stage of phagocytosis?
a. movement of phagocytes towards chemical attractants (chemotaxis)
b. activation of resting phagocytes by inflamatory mediators
c. margination, rolling and adhesion
d. diapedesis
c. recognition attachment, attachement of phagocyte to pathogen
d. ingestion
7. pathogen killing and degradation
b.activation of resting phagocytes by inflamatory mediators
what happens after margination, rolling and adhesion ?
a. movemeny of phagocytes towards chemical attractants (chemotaxis)
b. recognition attachment
c. ingestion
d. killing and degradation
e. diapedesis
e.diapedesis
what happens after diapedesis?
a. pathogen killing and degradation
b. ingestion
c. recognition attachment, attachment of phagocyte to pathogen
d. chemotaxis
e. rolling , margination and adhesion
c.recognition attachment, attachment of phagocyte to pathogen
what cell has red cytoplasmic granules?
a. basophils
b. eosinophils
c. neutrophils
d. lymphocytes
b.eosinophils
what cell has purple cytoplasmic granules?
a. basophils
b. eosinophils
c. neutrophils
d. lymphocytes
a.basophils
Which cell type migrates to areas of infection via chemotaxis?
a. basophils
b. eosinophils
c. neutrophils
d. lymphocytes
b.eosinophils
true or false eosinophils are capable of phagocytosis but are less active than neutrophils in this role?
true
how do eosinophils defend against larger parasites?
a. release toxins
b. granulation
c. degranulation
d. phagocytosis
c.degranulation
In allergic disease eg asthma or hay fever which cell type is most liklely to be increased?
a. basophils
b. eosinophils
c. neutrophils
d. lymphocytes
b.eosinophils
patient has raised eosinophils on a white cell count which condition is most likley?
a. allergic disease
b. bacterial infection
c. genetic mutation
d. viral infection
a.allergic disease
what does prolonged high levels of eosinophils lead to?
a. fever
b. nausea
c. sepsis
d. tissue damage
d.tissue damage
which is the least active phagocyte?
a. neutrophils
b. eosinophils
c. basophils
c.basophils
what do basophils do at the site of infection?
a. phagocytosis
b. release chemicals
d. degranulate
e. release antibodies
b.release chemicals
which type of cell releases mediators of inflammation eg histamines and anticoagulant eg heparin at the site of infection?
a. basophils
b. eosinophils
c. neutrophils
d. lymphocytes
a.basophils
what shape is the nucleus of lymphocytes?
a. bilobed
c. kidney u shape
d. polymorphonuclear
e. spherical
e.spherical
what colour is the cytoplasm of lymphocytes?
a. purple
b. pale blue
c. pink
d. red
e. dark blue
b. pale blue
Which type of lymphocyte attacks invaders outside of the cell?
a. T killer cells
b. T cells
c. B cells
c. B cells
true or false lymphocytes are involved in phagocytosis
false
Which of these best describes the role of T cells?
a. attack foreign cells directly and coordinate the immune response by increasing/decreasing other lymphocytes
b. attachment of antigen to surface receptor leads to activation, become plasma cells and secrete antibodies, become memory cells
c. kill infected/cancerous cells, cutoplasmic granule contents released, perforate cell membrane and cause initiation of apoptosis
a.attack foreign cells directly and coordinate the immune response by increasing/decreasing other lymphocytes
what cell destroys virally infected cells and tumour cells?
a. regulatory T cells
b. helper T cells
c. cytotoxic t cell
d. memory t cell
c.cytotoxic t cell
which of these best describes the role of cytotoxic t cells ?
a. destroy virally infected cells and tumour cells, implicated in transplant rejection
b. assist other white blood cells, including maturation of B cells to plasma cells and memory B cells, activation of cytotoxic t cells and macrophages
c. crucial for maintenance of immunological tolerance
d. persist long time after infection has resolved
a.destroy virally infected cells and tumour cells, implicated in transplant rejection
which white blood cell is raised in transplant rejection?
a. eosinophil
b. helper t cell
c. cytotoxic t cell
d. b lymphocye
c.cytotoxic t cell
which of these best describes the role of helper t cells?
which of these best describes the role of cytotoxic t cells ?
a. destroy virally infected cells and tumour cells, implicated in transplant rejection
b. assist other white blood cells, including maturation of B cells to plasma cells and memory B cells, activation of cytotoxic t cells and macrophages
c. crucial for maintenance of immunological tolerance
d. persist long time after infection has resolved
b.assist other blood cells in immunological processes, B cell maturation into plasma cells and memory b cells and activation of cytoxic t cells and macrophages