Physiology - leucocytes and plasma proteins Flashcards

1
Q

which of these is not a function of white blood cells?

a. carrying O2
b. immune response
c. inflammatory response
d. disposal of damaged and aging cells

A

a.carrying O2

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2
Q

what is the cfirst stage of phagocytosis?

a. movement of phagocytes towards chemical attractants (chemotaxis)
b. activation of resting phagocytes by inflamatory mediators
c. margination, rolling and adhesion
d. diapedesis
c. recognition attachment, attachement of phagocyte to pathogen
d. ingestion
7. pathogen killing and degradation

A

b.activation of resting phagocytes by inflamatory mediators

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3
Q

what happens after margination, rolling and adhesion ?

a. movemeny of phagocytes towards chemical attractants (chemotaxis)
b. recognition attachment
c. ingestion
d. killing and degradation
e. diapedesis

A

e.diapedesis

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4
Q

what happens after diapedesis?

a. pathogen killing and degradation
b. ingestion
c. recognition attachment, attachment of phagocyte to pathogen
d. chemotaxis
e. rolling , margination and adhesion

A

c.recognition attachment, attachment of phagocyte to pathogen

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5
Q

what cell has red cytoplasmic granules?

a. basophils
b. eosinophils
c. neutrophils
d. lymphocytes

A

b.eosinophils

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6
Q

what cell has purple cytoplasmic granules?

a. basophils
b. eosinophils
c. neutrophils
d. lymphocytes

A

a.basophils

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7
Q

Which cell type migrates to areas of infection via chemotaxis?

a. basophils
b. eosinophils
c. neutrophils
d. lymphocytes

A

b.eosinophils

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8
Q

true or false eosinophils are capable of phagocytosis but are less active than neutrophils in this role?

A

true

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9
Q

how do eosinophils defend against larger parasites?

a. release toxins
b. granulation
c. degranulation
d. phagocytosis

A

c.degranulation

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10
Q

In allergic disease eg asthma or hay fever which cell type is most liklely to be increased?

a. basophils
b. eosinophils
c. neutrophils
d. lymphocytes

A

b.eosinophils

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11
Q

patient has raised eosinophils on a white cell count which condition is most likley?

a. allergic disease
b. bacterial infection
c. genetic mutation
d. viral infection

A

a.allergic disease

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12
Q

what does prolonged high levels of eosinophils lead to?

a. fever
b. nausea
c. sepsis
d. tissue damage

A

d.tissue damage

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13
Q

which is the least active phagocyte?

a. neutrophils
b. eosinophils
c. basophils

A

c.basophils

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14
Q

what do basophils do at the site of infection?

a. phagocytosis
b. release chemicals
d. degranulate
e. release antibodies

A

b.release chemicals

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15
Q

which type of cell releases mediators of inflammation eg histamines and anticoagulant eg heparin at the site of infection?

a. basophils
b. eosinophils
c. neutrophils
d. lymphocytes

A

a.basophils

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16
Q

what shape is the nucleus of lymphocytes?

a. bilobed
c. kidney u shape
d. polymorphonuclear
e. spherical

A

e.spherical

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17
Q

what colour is the cytoplasm of lymphocytes?

a. purple
b. pale blue
c. pink
d. red
e. dark blue

A

b. pale blue

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18
Q

Which type of lymphocyte attacks invaders outside of the cell?

a. T killer cells
b. T cells
c. B cells

A

c. B cells

19
Q

true or false lymphocytes are involved in phagocytosis

A

false

20
Q

Which of these best describes the role of T cells?

a. attack foreign cells directly and coordinate the immune response by increasing/decreasing other lymphocytes
b. attachment of antigen to surface receptor leads to activation, become plasma cells and secrete antibodies, become memory cells
c. kill infected/cancerous cells, cutoplasmic granule contents released, perforate cell membrane and cause initiation of apoptosis

A

a.attack foreign cells directly and coordinate the immune response by increasing/decreasing other lymphocytes

21
Q

what cell destroys virally infected cells and tumour cells?

a. regulatory T cells
b. helper T cells
c. cytotoxic t cell
d. memory t cell

A

c.cytotoxic t cell

22
Q

which of these best describes the role of cytotoxic t cells ?

a. destroy virally infected cells and tumour cells, implicated in transplant rejection
b. assist other white blood cells, including maturation of B cells to plasma cells and memory B cells, activation of cytotoxic t cells and macrophages
c. crucial for maintenance of immunological tolerance
d. persist long time after infection has resolved

A

a.destroy virally infected cells and tumour cells, implicated in transplant rejection

23
Q

which white blood cell is raised in transplant rejection?

a. eosinophil
b. helper t cell
c. cytotoxic t cell
d. b lymphocye

A

c.cytotoxic t cell

24
Q

which of these best describes the role of helper t cells?

which of these best describes the role of cytotoxic t cells ?

a. destroy virally infected cells and tumour cells, implicated in transplant rejection
b. assist other white blood cells, including maturation of B cells to plasma cells and memory B cells, activation of cytotoxic t cells and macrophages
c. crucial for maintenance of immunological tolerance
d. persist long time after infection has resolved

A

b.assist other blood cells in immunological processes, B cell maturation into plasma cells and memory b cells and activation of cytoxic t cells and macrophages

25
Q

which of these best describes the role of regulatory t cells ?

a. destroy virally infected cells and tumour cells, implicated in transplant rejection
b. assist other white blood cells, including maturation of B cells to plasma cells and memory B cells, activation of cytotoxic t cells and macrophages
c. crucial for maintenance of immunological tolerance
d. persist long time after infection has resolved

A

c.crucial for maintenance of immunological tolerance

26
Q

which of these best describes the role of memory t cells ?

a. destroy virally infected cells and tumour cells, implicated in transplant rejection
b. assist other white blood cells, including maturation of B cells to plasma cells and memory B cells, activation of cytotoxic t cells and macrophages
c. crucial for maintenance of immunological tolerance
d. persist long time after infection has resolved

A

d.persist a long time after infection has resolved

27
Q

what activates B cells?

a. chemotaxis
b. attachment of antigen to surface receptor
c. memory t cells

A

b. attachment of antigen to surface receptor

28
Q

which type of lymphocyte is responsible for killing infected/cancerous cells?

a. Natural killer cells
b. b lymphocyes
c. t helper cells
d. regulatory t cell
e. memory t cell

A

a.natural killer cells

29
Q

Which of these best describes the role of natural killers?

a. destroy virally infected cells and tumour cells, implicated in transplant rejection
b. assist other white blood cells, including maturation of B cells to plasma cells and memory B cells, activation of cytotoxic t cells and macrophages
c. crucial for maintenance of immunological tolerance
d. persist long time after infection has resolved
e. release cytoplasmic granule contents, perforate cell membrane, cause cells to initate apoptosis

A

e.release cytoplasmic granule contents, perforate cell membrane, cause cells to initate apoptosis

30
Q

what shape is the nucleus of a monocyte?

a. kidney shaped
b. bilobed
d. spherical

A

a.kidney shaped

31
Q

true or false monocytes play a role on phagocytes

A

true

32
Q

which type of cell attracts other wbc and fibroblasts then after 72 hours enter tissues and become macrophages

a.neutrophils
b.lymphocytes
c.leucocytes
d,monocytes

A

d.monocytes

33
Q

Which cell is able to respond quickly after any
subsequent encounter with the same antigen?
A. memory cell
B. helper T cell
C. plasma cell
D. basophil
E. antigen-presenting cell

A

a. memory cell

34
Q
Which molecules are secreted by leucocytes 
and macrophages and result in a fever?
A. heparins
B. pyrogens
C. histamines
D. antibodies
E. keratins
A

b.pyrogens

35
Q

which of these is not a component of the plasma?

a. plasma proteins
b. organic nutrients and wastes
c. electrolytes
d. water
e. platelets

A

e.platelets

36
Q

Which of these substances contains negatively charged proteins?

a.ICF
b.CSF
c.plasma
d,interstitial fluid

A

c.plasma

37
Q

What type of protein makes up 60% of the total?

a. globulins
c. albumin
d. fibrinogen
e. keratin

A

c.albumin

38
Q

which plasma protein exerts a plasma osmotic pressure?

a. fibrinogen
b. globulin
c. albumin

A

c.albumin

39
Q

what plasma protein carries fats, amino acids, enzymes, drugs and is non specific?

a. fibrinogen
b. globulin
c. albumin

A

c.albumin

40
Q

which plasma protein carriers ions, hormones and vitamins?

a. fibrinogen
b. globulin
c. albumin

A

b.globulin

41
Q

which plasma protein makes up 35% of the total?

a. fibrinogen
b. globulin
c. albumin

A

b.globulins

42
Q

which plasma protein makes 4% of the total?

a. fibrinogen
b. globulin
c. albumin

A

a.fibrinogen

43
Q

which plasma protein has an immune function?

a. fibrinogen
b. globulin
c. albumin

A

b. globulin

- gamma globulins are antibodies

44
Q

which plasma protein has a role in blood clotting?

a. fibrinogen
b. globulin
c. albumin

A

a.fibrinogen