PATHOMA- vasculitis Flashcards
vasculitis is defined as
inflammation of the blood vessel wall
general symptoms of vasculitis
non specific inflammation symptoms
organ ischemia
vasculitis is split into
vessel size
large vessel vasculitis type
temporal (giant cell) arteitis
takayas arteitis
*Aorta an its major branchs
Medium vessel vasculitis type
polyarteritis nodosa
kawasaki disease
*muscular art that supply organs
Small vessel vasculitis type
Wegener granulomatosis
Microscpoic Polyangitis
Chug Strous Small Cell
Henoch–Schönlein purpura
Adults over 50
Temporal artery (HA)
Opthalmic artery (vision chnages)
Jaw Claudation
temporal (giant cell) arteitis
Adults under 50
usually Asian women
Affctes proximally
neuro involvement
takayas arteitis
Elevated ESR
Granulomitis Inflamation
Presence of giant cells on biopsy
temporal (giant cell) arteitis/takayas arteitis
Young Adult Necrotizing Lungs are spared affects large organs related to Hep B
Polyaritis Nodosa
Asain children under 4
non-specific symptoms
Coronary Art
Can lead to MI Aspirin as Rx
kawasaki disease
takayas arteitis
Adults under 50
usually Asian women
Affctes proximally
neuro involvement
Never has lung symptoms
Nodules of fibrosis on artery tissue
FATAL without corticosteriod treatment
Polyaritis Nodosa
Wegener Granulomatosis
Wegener Granulomatosis
ANCA Test
Slide with neutrophils
add pt serum
if serum has AB, it will bind
P-ANCA- binds near nucleus
C-ANCA- binds in cytoplasm
