BL- COAG MADE EASY

Question 1

The PT and the PTT pathway meet at factor:

Answer 1

X, because “X” marks the spot

Question 2

Factor______is a cofactor for factor X, and you can remember this because ______fits into the notch of the X

Answer 2

V

Question 3

Factor Xa converts prothrombin (Factor II) into ______, the most important enzyme on the planet

Answer 3

thrombin

Question 4

Thrombin, among other things, converts the soluble molecule fibrinogen into a:

Answer 4

solid fibrin clot

Question 5

The Common Pathway money memory device

Answer 5

$ Small Bills: 10, 5, 2, 1
V + X
II = prothrombin
I = fibrinogen

Question 6

You can remember the factors in the common pathway by remembering the bills in your wallet smaller than a ______. Don’t forget the $2 bill !!

Answer 6

$20

Question 7

Factor Xa converts ______ (Factor II) into thrombin, the most important enzyme on the planet

Answer 7

prothrombin

Question 8

PT has one less letter than PTT, and PT values are shorter than PTT values, because the pathway is______

Answer 8

shorter

Question 9

Well, just remember that the PTT is a basic ______of hematology.

Answer 9

TENET

T=12
E=11
N=9
E=8
T= 10

Question 10

Factor______converts prothrombin (Factor II) into thrombin, the most important enzyme on the planet

Answer 10

Xa

Question 11

_______ converts the soluble molecule fibrinogen into a solid fibrin clot

Answer 11

Thrombin

Question 12

Deficiency of___________will prolong the PT but not the PTT

Answer 12

Factor VII

Question 13

Deficiencies of Factors ____________ will prolong the PTT and not the PT.

Remember that factor 10 is in the common pathway, and affects BOTH the PT and the PTT

Answer 13

12, 11, 9 and 8

Question 14

Deficiencies of factor XI, IX, VIII, VII. X, V, prothrombin and fibrinogen are clinically significant.

Answer 14

Inhibitors of these factors are clinically significant for bleeding.

Question 15

Deficiency of Factor XII, and the presence of the lupus anticoagulant are not?

Answer 15

clinically significant.