BL- Cohan 1

Question 0

Th17

Answer 0

Makes interleukin 17, IL 17.
Causes very bad inflammation for toughest agents

Pro inflammatory

Question 1

Th1 job

Answer 1

Delayed hypersensitivity
Attracts m1 macrophages
Release ifn gama

Question 2

Th2

Answer 2

Helper T cell
Longer development than th1

Brings m2 macrophages (less angry than m1)
Can encourage fibrous capsule growth

Question 3

Th2 fx and cytokine

Answer 3

Scarring
Attracts eosinophils
IL4

Question 4

Tfh

Answer 4

Interacts with developing B cells to “switch”

Question 5

Treg function

Answer 5

Helper cell

Tells all other helper cells to stop responding and making cytokines

“Wiser older sibling”

Question 6

CTL name

Answer 6

Killer cell

Cytotoxic t lymphocyte

Question 7

CD8 mhc class

Answer 7

Cd8 interacts with class one mhc

Question 8

CD4 MHC Class

Answer 8

Cd4 interact with class two MHC

Question 9

CD4 Is on what kind of cell

Answer 9

T helper

Question 10

CD8 are on what cell

Answer 10

CTL

Question 11

MHC Class two chains

Answer 11

Two chains, both bind. Alpha and beta

Question 12

Class one MHC is on…

Answer 12

Every nucleated cell has class one MHC on their surface

Question 13

CTL can see ____ cells

Answer 13

CTL can see All Cells. CTL sees class one MHC, and MHC is on all cells.

Question 14

CLASS TWO MHC

Basics

Answer 14

T helper cells see class two. 
Three cells make class two 

Dendritic
Macrophage
B Cells

Question 15

Professional Antigen Presenting Cells

Answer 15

Dendritic
Macrophages
B cells

Class two MHC cells

Question 16

B Cell MHC reaction with Tfh

Answer 16

Antigen binds
B cell chops it up 
Presents peptide on MHC 2
Tfh interacts
Tfh activates B cell

Question 17

T Independent antigen

Answer 17

Usually carbs
Activates B cell with out T cell
B cell can only make IgM like this

Question 18

HLA D cells

Answer 18

MHC Class 2 cells

Dendritic, macrophage, B cell

Question 19

Hemosiderin

Answer 19

is most commonly found in macrophages and is especially abundant in situations following hemorrhage

Question 21

Ankylosing spondylitis

Answer 21

Strong genetic inflammation activists with IL1

chronic inflammatory disease of the axial skeleton

involves CD8 T cells, which interact with HLA-B.

Question 22

Natural, active immunity

Answer 22

usual immunity that results from real-life exposure to a pathogen.

Question 23

Natural, passive immunity

Answer 23

fetus gets IgG
passively across the placenta from its mother

the baby gets IgA in mother’s milk if she nurses it

Question 24

Artificial, active immunity

Answer 24

: immunity resulting from intentional immunization with vaccines, toxoids, or
other antigenic preparations.

Question 25

Artificial, passive immunity

Answer 25

the use of immune serum or purified antibodies to protect a patient at risk
from a particular disease

Question 26

tetanus, immunization offers close to _____ protection

Answer 26

100%

Question 27

Cause of sherocytosis

Answer 27

Spleen notices membrane defect and pinches some off

Question 28

Glucose-6-phosphate dehydrogenase deficiency

Answer 28

enzyme involved in the pentose phosphate pathway that is especially important in the red blood cell.

genetic condition that predisposes to hemolysis

Question 29

Natural Killer cell activity is enhanced by

Answer 29

IL-2

Question 30

C3b

Answer 30

opsonization

Question 31

C3a, C5a

Answer 31

anaphylaxis

Question 32

C5a

Answer 32

Neutriphil chemotaxis

Question 33

C5b

Answer 33

Cytolysis by Mac

Question 34

First antibody responder?

Answer 34

IgM

Question 35

Second Antibody responder

Answer 35

IgG

Question 36

Best compliment activator of the antibodies?

Answer 36

IgM

Question 37

C1q complement needs to bind how many FCs

Answer 37

2 to activate

Question 38

Coombs Test

Answer 38

detects antibodies that are already attached to red blood cells

Question 39

Indirect Coombs Tets

Answer 39

detect very low concentrations of antibodies present in a patient’s plasma/serum prior to a blood transfusion.