PATHOMA- derm Flashcards
IgG vs. Desomosomes
creates blister between basal cell layer and epidermis of the skin and oral mucosa
Pemphigous Vulgaris
Akantholysis
separation of the keritinocytes
IgG vs. Hemidesomsomes
Blister between dermis and epidermis
Bullous Pemhigoid
Blister involving skin and oral mucoas?
PV- Pemphigous Vulgaris
BP does NOT affect oral areas
Tense, non-easily ruptured blister?
BP- Bullous Pemhigoid
IgA deposite at tip of the dermal papilia
Small vessical
Asc. w/ celiac
Dermatitis Herpatiformis uy
Basal Cell Carcinoma
Malignent
Affects BCL- often upper lip
UVB risk factor
BCC Rx?
Surgical excision
Squamous Cell Carcinoma
Malignant Ulcer/mass
UVB risk factor
Lower lip
SCC is asc. w/?
Arsenic poisoning
Immunosupresion
Actinic Keratosis
SCC precurser
Hyperkeratotic
Karatoacanthoma: rapid onset/regreesion of cup SCC
Seborrheic Keratois
squamous
raised discolored plaque
usually affects elderly
Leser Trelate sign
rapid onset of many Seborrheic Keratois.
Indicates GI carcinoma
Dark thickening of the skin
related to insulin resistance
Acanthosis nigracans
Melanocytes
create pigmentation of the skin
BCL
Vitalgo
autoimmune destruction of melanocyte
creates localized depig
Neoplasam of melanocytes
can be congenital or aquired
Will grow hair
Nevus (mole)
Melenoma
neoplasam of melanocytes
Common COD for skin cancer
UVB damage
“ABCDE” helps differ this from a mole
Melanoma prognosis
Depth of invasion
Melenoma subtypes
Lenitgo maligna melenoma
Superficial spreading
Nodular =(
Acral
Nodular Melenoma
Early vertical growth of tumor
spreads faster
Pushes up epidermis making a nodule
poor prog
Acral Lentiginous
common in dark skin
affects soles/palm
no sunlight risk factor
Impetigo
usually from S. Aures or Strep pyogenes
Honey colored crust
common in children/on the face
Cellulitis
usually from S. Aures or Strep pyogenes
red, tender, swollen
Common risk factors: surgery, trama
*may progress to nec. fasc.
Verruca
aka a wart
often from HPV
common on hands/feet
