PATHOMA- Derm inflam

Question 1

Layers of the Epidermis

top to bottome

Answer 1

Corneum
Lucidum
Granulosum
Spinosum
Basale
~BM~
Dermis

Question 2

Stratum corneum contains?

Answer 2

Keratin

Question 3

Stratum spinosum contains?

Answer 3

Desmosomes

Question 4

a cell structure specialized for cell-to-cell adhesion. A type of junctional complex, they are localized spot-like adhesions randomly arranged on the lateral sides of plasma membranes.

Answer 4

Desmosomes

Question 5

key structural material making up the outer layer of human skin. It is also the key structural component of hair and nails.

Answer 5

Keratin

Question 6

The dermis contains

Answer 6

adnexal structures 
Blood vessels
sweat glands 
sebaceous  glands 
connective tissue

Question 7

sebaceous glands

Answer 7

microscopic exocrine glands in the skin that secrete an oily or waxy matter, called sebum, to lubricate and waterproof the skin and hair of mammals

Question 8

The basal cells functions to

Answer 8

Stem cell layer

Creates new epidermis

Question 9

An itchy inflammation of the skin

also known as atopic eczema or eczema

Answer 9

Atopic dermatitis

Question 10

Dermatitis means

Answer 10

inflammation of the skin

Question 11

Atopic dermatitis key points

Answer 11

s/s
pruitic 
erthemitic 
oozing
vesicles
edema

face/flexor
rx: topical steroids

Question 12

results from exposure to allergens or irritants

Answer 12

Contact dermatitis

Question 13

caused by chemical irritants and those caused by physical irritants.

Answer 13

irritant contact dermatitis

Question 14

manifestation of an allergic response caused by contact with a substance

Answer 14

allergic contact dermatitis

Question 15

Common irritants in irritant contact dermatitis

Answer 15

nickel
poison ivy
detergents
drugs

rx: remove irritant from exposure
Topical steriods

Question 16

chronic inflammation of hair follicle and sebacous glands

Answer 16

acne vulgaris

Question 17

acne vulgaris is caused by?

Answer 17

Hormones leading to increased sebum
excess keratin
*blocked follicle leading to infection by p. acne

Question 18

Inflammation in Acne is the result of?

Answer 18

lipase breaks down xs sebum

release of inflammatory mediators

Question 19

chronic, relapsing/remitting, immune-mediated systemic disease characterized by skin lesions including red, scaly patches, papules, and plaques, which usually itch.

Answer 19

Psoriasis

Question 20

Psoriasis lesions are?

Answer 20

well circumscribed
salmon colored
silver scales

also shows nail pitting

Question 21

Psoriasis are located?

Answer 21

extensor surfaces

scalp

Question 22

Psoriasis is caused by?

Answer 22

possibly autoimmune
excess keratinocytes
HLA-C ass.

Question 23

diffuse epidermal hyperplasia (thickening of the skin).

Answer 23

Acanthosis

Question 24

Cellulitis morphology

Answer 24

warm, tender, red, patch, plaque

Question 25

Cellultisis loction

Answer 25

dermis/sub q tissue

Question 26

Dermatitis location

Answer 26

epidermis/ dermis

Question 27

infection of the upper dermis and superficial lymphatics, usually caused by streptococcus bacteria on scratches or otherwise infected areas

Answer 27

Erysipelas

Question 28

rysipelas is more superficial than cellulitis, and is typically more raised and _______

Answer 28

demarcated.

Question 29

Erysipelas location

Answer 29

dermis | minimal sub q

Question 30

Stasis dermis location?

Answer 30

lower leg

Question 31

Seborrheic dermatitis location?

Answer 31

scalp

Question 32

Atopic dermatitis location?

Answer 32

flexor

Question 33

Psoriasis location?

Answer 33

extensor *may have arthritis

Question 34

Lower ext. edema

Answer 34

statis dermatitis

Question 35

Malassezia furfur

Answer 35

Seborrheic dermatitis

Question 36

Malassezia is a genus of fungi. Malassezia is naturally found on the:______

Answer 36

skin surfaces

Question 37

Filaggrin

Answer 37

a filament-associated protein that binds to keratin fibers in epithelial cells.

Question 38

Atopic derm etiology

Answer 38

Filaggrin etiology

Question 39

Atopic derm is ass w/?

Answer 39

asthma | alleric rhinitis

Question 40

Allergic contact derm is a _____ rxn

Answer 40

Delayed hypersensitivity

Question 41

Allergic contact derm is confirmed by?

Answer 41

patch testing

Question 42

______ may be ass. w/ cardiovascular disease

Answer 42

Psoriasis

Question 43

``` Prurtic Planar Polygonal Purple Papule ```

Answer 43

Lichen Planus

Question 44

HEP C related inflammatory rash

Answer 44

Lichen Planus