P7 - Erythrocytes Part 2

Question 1

Anaplasma marginale significance

Answer 1

• marginal bodies in first few days of anemia

- resemble Howell-Jolly but are on margin of cell

Question 2

Cytauxzoon felis significance

Answer 2

• tick born
• part of life cycle
• go from ring form to cross

Question 3

babesia sp. identification (2)

Answer 3

• B. canis - tear drop shaped

- B. gibsoni - ring form

Question 4

mycoplasma haemofelis formation

Answer 4

• grows on cell

- cocci and rings on surface

Question 5

anisocytosis

Answer 5

• different sizes of cells

Question 6

macrocytes

Answer 6

• increase diameter -> increase volume

Question 7

microcytes

Answer 7

• decreased cell volume

Question 8

poikilocyte

Answer 8

• cells of different shapes

Question 9

acanthocyte

Answer 9

• spur

- 1-20 irregularly spaced membrane projections (usually blunt)

Question 10

acanthocyte formation

Answer 10

• RBC trauma or excess membrane lipid

Question 11

codocyte

Answer 11

• hat/bullseye

- central focus of Hgb surrounded by ring of pallor

Question 12

codocyte formation

Answer 12

• excess membrane relative to amount of Hgb

- usually with regenerative anemia

Question 13

eccentrocyte

Answer 13

• condensed portion that stains dark

Question 14

eccentrocyte formation

Answer 14

• oxidative damage to RBC membrane and Hgb

Question 15

echinocyte

Answer 15

• spiny (regular all the way around)

Question 16

echinocyte formation

Answer 16

• membrane changes

- dying artifact

Question 17

elliptocyte (ovalocyte)

Answer 17

• elliptical or oval

Question 18

keratocyte

Answer 18

• horn

- notched cell with 1 to 2 horn-like projections (looks like a bite)

Question 19

keratocyte formation

Answer 19

• intravascular RBC trauma

Question 20

pyknocyte

Answer 20

• spheroidal cell with condensed Hgb

Question 21

pyknocyte formation

Answer 21

• oxidative damage to membrane and Hgb

Question 22

schizocyte

Answer 22

• triangular, comma-shaped or round RBC fragment

Question 23

schizocyte formation

Answer 23

• intravascular RBC trauma

Question 24

spherocyte

Answer 24

• round

Question 25

spherocyte formation

Answer 25

• removal of membrane or defective membrane

Question 26

yellow/orange plasma in herbivores due to

Answer 26

• plant pigments

Question 27

erythrocyte parasites causing hemoglobinemai and hemoglobinuria (3)

Answer 27

• Babesia
• Theileria
• Rickettsiae

Question 28

erythrocyte parasite causing hemobartonella

Answer 28

• mycoplasma hemofelis

Question 29

impedance cell counters ID erythrocytes by

Answer 29

• volume

Question 30

optical or laser flow cell cytometers ID erythrocytes by

Answer 30

• light scatter

Question 31

centrifugation analysis ID erythrocytes by

Answer 31

• % blood volume occupied by cells

Question 32

exceptions to the normal total increase or decrease in Hct [Hgb] and [RBC] associated with increase RBC mass (3)

Answer 32

• different sizes of RBC
• hypochromic RBC with less Hgb
• in vitro hemolysis (Hbg not changed)