P10 - Leukocyte Flashcards

1
Q

neutrophils pools in marrow

A
  • ProNP - proliferation neutrophil pool
  • MatNP - maturation neutrophil pool
  • SNP - storage neutrophil pool
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2
Q

neutrophil pools in blood

A
  • MNP - marginated neutrophil pool

- CNP - circulating neutrophil pool

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3
Q

three things that happen to create a neutrophilia

A
  • increased [neutrophils]
  • shift from MNP to CNP
  • decrease migration to tissues
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4
Q

left shift

A
  • increase [nonsegmented neutrophils]
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5
Q

regenerative left shift

A
  • segs > nonsegs
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6
Q

degenerative left shift

A
  • nonsegs > segs
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7
Q

clinical significance of left shift

A
  • acute inflammatory reaction
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8
Q

clinical significance of regenerative left shift

A
  • adequate response to inflammatory disorder
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9
Q

clinical significance of degenerative left shift

A
  • inadequate response to inflammatory disorder
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10
Q

right shift

A
  • increase [hypersegmented neutrophils]
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11
Q

clinical significance of right shift

A
  • glucocortiocid hormones decrease emigration of neutrophils to tissues
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12
Q

lymph node path

A
  • from blood into lymph node and back
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13
Q

tissue path

A
  • blood to tissues to lymph node and back into blood
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14
Q

blood path

A
  • back and forth through the capillaries
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15
Q

cell counters that does not ID abnormal cells correctly and does not detect organisms

A
  • electronic cell counters
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16
Q

leukocytosis

A
  • elevated white cell concentration
17
Q

leukogram pattern:

  • increase total WBC
  • increase segs
  • increase non segs
  • decrease lymphocytes
  • WRI-or increased monocytes
  • decreased-or WRI eosinophils
A
  • acute inflammatory
18
Q

leukogram pattern:

  • increase total WBC
  • increase segs
  • WRI-or increased non segs
  • increase lymphocytes
  • increased monocytes
  • WRI - eosinophils
A
  • chronic inflammatory
19
Q

leukogram pattern:

  • increased total WBC
  • increase segs
  • WRI-or increased non segs
  • decreased lymphocytes
  • increased monocytes
  • decreased eosinophils
A
  • glucocortiocid
20
Q

leukogram pattern:

  • increase total WBC
  • increase segs
  • WRI non segs
  • increase lymphocytes
  • WRI-or increased monocytes
  • WRI eosinophils
A
  • physiologic leukocytosis