ORGANOTROPIC AGENTS - Hypertensive (anti-hypotensive) drugs. Drugs influencing cerebral blood flow. Anti-migraine agents

Question 1

The main principle of shock treatment is

Answer 1

To improve the peripheral blood flow

Question 2

Drug which increases cardiac output

Answer 2

Noradrenalin

Question 3

The synthetic vasoconstrictor having an adrenomimic effect

Answer 3

Phenylephrine

Question 4

Indicate the vasoconstrictor of endogenous origin

Answer 4

Angiotensinamide

Question 5

Which type of receptors can be activated by angiotensinamide

Answer 5

Angiotensin’s receptors

Question 6

General unwanted effects of vasoconstrictors is

Answer 6

Decrease of peripheral blood flow

Question 7

For increasing blood pressure in case of low cardiac output the following agents must be used

Answer 7

Positive inotropic drugs

Question 8

Positive inotropic drug of glycoside structure

Answer 8

Digoxin

Question 9

Positive inotropic drug of non-glycoside structure

Answer 9

Dobutamine

Question 10

Dopamine at low doses influences mainly

Answer 10

Dopamine receptors (leads to vasodilation of renal and mesenterial vessels)

Question 11

Dopamine at medium doses influences mainly

Answer 11

Beta-1 adrenoreceptors (leads to enhanced cardiac output)

Question 12

Dopamine in high doses influences mainly the

Answer 12

Alfa-adrenoreceptors (leads to peripheral vasoconstriction)

Question 13

Group of drugs for treatment of shock with hypovolaemia (reduced circulating blood volume)

Answer 13

Plasmoexpanders

Question 14

Group of drugs for chronic hypotension treatment

Answer 14

Analeptics and tonics

Question 15

Indicate the group of drugs influencing the cerebral flow

Answer 15

• Ca-channel blockers
• Derivatives of GABA
• Derivatives of Vinca minor plant

Question 16

Grug influencing the blood flow which is related to antiplatelet agents

Answer 16

Aspirin

Question 17

Which drugs is related to anticoagulants and may be useful in disorders of cerebral circulation?

Answer 17

Heparin

Question 18

Indicate the drugs which are Ca-channel blockers influencing the brain blood flow

Answer 18

Nimodipine, Cinnarizine

Question 19

Indicate the drugs influencing the blood flow in the brain - derivatives of GABA

Answer 19

Aminalon, Picamilon

Question 20

Indicate the drug - Vinca minor alcaloid

Answer 20

Vinpocetine

Question 21

Drug – a derivative of Ergot

Answer 21

Nicergoline

Question 22

Indicate the nootropic agent useful in disorders of brain circulation

Answer 22

Pyracetam

Question 23

What is the main action of GABA derivatives in disorders of brain circulation?

Answer 23

Stimulation of the metabolic processes in neurons

Question 24

Appropriate mechanism of vinpocetine action

Answer 24

It dilates cerebral vessels and improves blood supply

Question 25

Antiaggregants are used in disorders of brain circulation for

Answer 25

Improving the microcirculation in cerebral tissue

Question 26

Migraine is a disorder connected with

Answer 26

Dysfunction of regulation of cerebral vessel tonus

Question 27

True or False. Main agents for acute migraine attack treatment are Ergot and indol derivatives and NSAID’s.

Answer 27

TRUE

Question 28

The following Indol derivative is used for treatment of acute migraine attack

Answer 28

Sumatriptan

Question 29

The following Ergot derivative is used for treatment of acute migraine attack

Answer 29

Ergotamine

Question 30

The derivative of lysergic acid for migraine attack prevention is

Answer 30

Methysergide