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Pharmacology > ORGANOTROPIC AGENTS - Drugs used in gastrointestinal diseases > Flashcards

ORGANOTROPIC AGENTS - Drugs used in gastrointestinal diseases Flashcards

1
Q

Tick the main approach of peptic ulcer treatment

A
  • Neutralization of gastric acid
  • Eradication of Helicobacter pylori
  • Inhibition of gastric acid secretion
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2
Q

Gastric acid secretion is under the control of

A
  • Histamine
  • Acetylcholine
  • Gastrin
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3
Q

Gastric acid secretion is not under the control of

A

Serotonin

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4
Q

Indicate the drug belonging to proton pump inhibitors

A

Omeprazole

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5
Q

The following agents intensify the secretion of gastric glands

A
  • Gastrin
  • Histamine
  • Carbonate mineral waters
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6
Q

The following agent do not intensify the secretion of gastric glands

A

Pepsin

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7
Q

Which drugs is an agent of substitution therapy?

A

Hydrochloric acid

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8
Q

Choose the drug which is a H2-receptor antagonist

A

Ranitidine

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9
Q

The following drugs are proton pump inhibitors

A
  • Pantoprozole
  • Omeprazole
  • Rabeprazole
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10
Q

Indicate the drug belonging to M1-cholinoblockers

A

Pirenzepin

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11
Q

Which drugs may cause reversible gynecomastia?

A

Cimetidine

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12
Q

True or False. Cimetidine has no effect on hepatic drug metabolism.

A

FALSE

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13
Q

Tick the drug forming a physical barrier to HCL and Pepsin

A

Sucralfate

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14
Q

Which drug is an analog of prostaglandin E1?

A

Misoprostole

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15
Q

Select the drug stimulating the protective function of the mucous barrier and the stability of the mucous membrane against damaging factors

A

Misoprostol

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16
Q

True or False. Antacids are weak bases that react with gastric hydrochloric acid to form salt and water.

A

TRUE

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17
Q

Antacids drugs

A
  • Maalox
  • Mylanta
  • Almagel
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18
Q

Are not Antacids drugs

A

Misoprostol

19
Q

Indicate the drug that cause metabolic alkalosis

A

Sodium bicarbonate

20
Q

Drug that causes constipation

A

Aluminium hydroxide

21
Q

The following drugs stimulate appetite

A
  • Vitamins
  • Bitters
  • Insulin
22
Q

The following drugs do not stimulate appetite

23
Q

True or False. Ethyl alcohol is an agent decreasing appetite.

24
Q

Fenfluramine

A

An anorexigenic agent affecting serotoninergic system

25
Q

The following drugs intensify gastrointestinal motility

A
  • Metoclopramide
  • Domperidone
  • Cisapride
26
Q

The following drugs do not intensify gastrointestinal motility

A

Papaverine

27
Q

True or False. Metoclopramide is a potent dopamine antagonist.

28
Q

Emetic drug of central action

A

Apomorphine hydrochloride

29
Q

The mechanism of Metoclopramide antiemetic action

A

D2-dopamine and 5-HT3-serotonin receptor blocking effect

30
Q

The emetic agent having a reflex action

A

Ipecacuanha derivatives

31
Q

The following drugs are antiemetics

A
  • Metoclopramide
  • Ondansetron
  • Chlorpromazine
32
Q

The following drugs are not antiemetics

A

Apomorphine hydrochloride

33
Q

Indicate an antiemetic agent which is related to neuroleptics

A

Prochlorperazine

34
Q

Drugs that reduces intestinal peristalsis

A
  • Loperamide
  • Methyl cellulose
  • Magnesium aluminium silicate
35
Q

Drugs that does not reduces intestinal peristalsis

36
Q

Indicate the laxative drug belonging to osmotic laxatives

A

Sodium phosphate

37
Q

The mechanism of stimulant purgatives is

A

Increasing motility and secretion

38
Q

Drug irritating the gut and causing increased peristalsis

A

Phenolphthalein

39
Q

The following drugs stimulate bile production and bile secretion

A
  • Cholenszyme
  • Oxaphenamide
  • Cholosas
40
Q

The following drugs do not stimulate bile production and bile secretion

41
Q

Stimulant of bile production of vegetable origin

42
Q

Select the drug which inhibits peristalsis

A

Loperamide

43
Q

The drug affecting the biliary system and relaxing Oddy sphincter

Pharmacology (41 decks)

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