CHEMOTHERAPEUTIC DRUGS - ANTIVIRAL AGENTS. AGENTS FOR CHEMOTHERAPY OF CANCER Flashcards
The following antiviral drugs are the analogs of nucleosides
Saquinavir
The drug, a derivative of adamantane
Rimantadine
The drug, a derivative of pyrophosphate
Foscarnet
The drug, inhibiting viral DNA synthesis
Acyclovir
The drug, inhibiting uncoating of the viral RNA
Rimantadine
The drug, inhibiting viral reverse transcriptase
Zidovudine
The drug, inhibiting viral proteases
Saquinavir
The drug of choice for herpes and cytomegalovirus infection treatment
Acyclovir
The drug which belongs to nonnucleoside reverse transcriptase inhibitors
Nevirapine
The following antiviral drugs are antiretroviral agents
- Zidovudine
- Zalcitabine
- Didanozine
The drug used for influenza A prevention
Rimantadine
The drug used for HIV infection treatment, a derivative of nucleosides
Zidovudine
The antiviral drug which belongs to endogenous proteins
Interferon alfa
The drug which belongs to nucleoside reverse transcriptase inhibitors
Didanosine
The following antiviral drugs are anti-influenza agents
- Amantadine
- Interferons
- Rimantadine
The unwanted effects of zidovudine
Anemia, neutropenia, nausea, insomnia
The unwanted effects of intravenous acyclovir infusion
Renal insufficiency, tremors, delerium
The drug that can induce peripheral neuropathy and oral ulceration
Zalcitabine
The unwanted effects of didanozine
Peripheral neuropathy, pancreatitis, diarrhea, hyperuricemia
The unwanted effects of indinavir
Nephrolithiasis, nausea, hepatotoxicity
The drug that can induce nausea, diarrhea, abdominal pain and rhinitis
Saquinavir
The following effects are disadvantages of anticancer drugs
- Low selectivity to cancer cells
- Depression of bone marrow
- Depression of immune system
Rational combination of anticancer drugs is used to
Provide synergism resulting from the use of anticancer drugs with different mechanisms combination
The anticancer alkylating drug, a derivative of chloroethylamine
Cyclophosphamide
The anticancer alkylating drug, a derivative of ethylenimine
Thiotepa
The group of hormonal drugs used for cancer treatment
Glucocorticoids and gonadal hormones
The anticancer alkylating drug, a derivative of alkylsulfonate
Busulfan
The anticancer drug of plant origin
Vincristine
Action mechanism of alkylating agents is
Producing carbonium ions altering DNA structure
The anticancer drug, a pyrimidine antagonist
Fluorouracil
Methotrexate is
A folic acid antagonist
The antibiotic for cancer chemotherapy
Doxorubicin
Fluorouracil belongs to
Antimetabolites
The action mechanism of anticancer drugs belonging to plant alkaloids
Mitotic arrest at a metaphase
General contraindications for anticancer drugs are
- Depression of bone marrow
- Acute infections
- Severe hepatic and/or renal insufficiency
Action mechanism of methotrexate is
Inhibition of dihydrofolate reductase
The anticancer drug belonging to inorganic metal complexes
Cisplatin
The indication for estrogens in oncological practice
Cancer of prostate
Enzyme drug used for acute leukemia treatment
Dihydrofolate reductase
The following drugs are derivatives of nitrosoureas
- Carmustine
- Lomustine
- Semustine
The group of drugs used as subsidiary medicines in cancer treatment
- Cytoprotectors
- Bone marrow growth factors
- Antimetastatic agents
Estrogen inhibitor
Tamoxifen
Antiandrogen drug
Flutamide
The drug belonging to aromatase inhibitors
Anastrozole
The drug belonging to gonadotropin-releasing hormone agonists
Leuprolide
