CHEMOTHERAPEUTIC DRUGS - ANTIVIRAL AGENTS. AGENTS FOR CHEMOTHERAPY OF CANCER Flashcards
The following antiviral drugs are the analogs of nucleosides
Saquinavir
The drug, a derivative of adamantane
Rimantadine
The drug, a derivative of pyrophosphate
Foscarnet
The drug, inhibiting viral DNA synthesis
Acyclovir
The drug, inhibiting uncoating of the viral RNA
Rimantadine
The drug, inhibiting viral reverse transcriptase
Zidovudine
The drug, inhibiting viral proteases
Saquinavir
The drug of choice for herpes and cytomegalovirus infection treatment
Acyclovir
The drug which belongs to nonnucleoside reverse transcriptase inhibitors
Nevirapine
The following antiviral drugs are antiretroviral agents
- Zidovudine
- Zalcitabine
- Didanozine
The drug used for influenza A prevention
Rimantadine
The drug used for HIV infection treatment, a derivative of nucleosides
Zidovudine
The antiviral drug which belongs to endogenous proteins
Interferon alfa
The drug which belongs to nucleoside reverse transcriptase inhibitors
Didanosine
The following antiviral drugs are anti-influenza agents
- Amantadine
- Interferons
- Rimantadine
The unwanted effects of zidovudine
Anemia, neutropenia, nausea, insomnia
The unwanted effects of intravenous acyclovir infusion
Renal insufficiency, tremors, delerium
The drug that can induce peripheral neuropathy and oral ulceration
Zalcitabine
The unwanted effects of didanozine
Peripheral neuropathy, pancreatitis, diarrhea, hyperuricemia
The unwanted effects of indinavir
Nephrolithiasis, nausea, hepatotoxicity
The drug that can induce nausea, diarrhea, abdominal pain and rhinitis
Saquinavir
The following effects are disadvantages of anticancer drugs
- Low selectivity to cancer cells
- Depression of bone marrow
- Depression of immune system
Rational combination of anticancer drugs is used to
Provide synergism resulting from the use of anticancer drugs with different mechanisms combination
The anticancer alkylating drug, a derivative of chloroethylamine
Cyclophosphamide