ORGANOTROPIC AGENTS - Antihypertensive drugs

Question 1

This drug reduces blood pressure by acting on vasomotor centers in the CNS

Answer 1

Clonidine

Question 2

The following are central acting antihypertensive drugs

Answer 2

• Methyldopa
• Clonidine
• Moxonidine

Question 3

A ganglioblocking drug for hypertension treatment is

Answer 3

Trimethaphan

Question 4

A sympatholythic drug

Answer 4

Guanethidine

Question 5

Drug with nonselective beta-adrenoblocking activity

Answer 5

Propranolol

Question 6

The selective blocker of beta-1 adrenoreceptors

Answer 6

Atenolol

Question 7

An alpha and beta adrenoreceptors blocker

Answer 7

Labetalol

Question 8

This drug inhibits the angiotensin-converting enzyme

Answer 8

• Captopril
• Enalapril
• Ramipril

Question 9

This drug is a directly acting vasodilator

Answer 9

Nifedipine

Question 10

Diuretic agent for hypertension treatment

Answer 10

Dichlothiazide

Question 11

This drug blocks alpha-1 adrenergic receptors

Answer 11

Prazosin

Question 12

This drug activates alpha-2 adrenergic receptors

Answer 12

Clonidine

Question 13

This drug is an inhibitor of renin synthesis

Answer 13

Propranolol

Question 14

This drug is a non-peptide angiotensin II receptor antagonist

Answer 14

Losartan

Question 15

This drug is a potassium channel activator

Answer 15

Diazoxide

Question 16

True or False about angiotensin II. It is a peptide hormone

Answer 16

TRUE

Question 17

True or False about angiotensin II. It stimulates the secretion of aldosterone

Answer 17

TRUE

Question 18

True or False about angiotensin II. Angiotensin I is almost as potent as angiotensin II

Answer 18

FALSE

Question 19

True or False about angiotensin II. It is a potent vasoconstrictor

Answer 19

TRUE

Question 20

This drug is contraindicated in patients with bronchial asthma

Answer 20

Propranolol

Question 21

This drug is converted to an active metabolite after absorption

Answer 21

Enalapril

Question 22

This drug routinely produces some tachycardia

Answer 22

Nifedipine

Question 23

True or False about vasodilators. Hydralazine causes tachycardia

Answer 23

TRUE

Question 24

True or False about vasodilators. Nifedipine is a dopamine receptor antagonist

Answer 24

FALSE

Question 25

True or False about vasodilators. Nitroprusside dilates both arterioles and veins

Answer 25

TRUE

Question 26

True or False about vasodilators. Minoxidil can cause hypertrichosis

Answer 26

TRUE

Question 27

True or False about verapamil. It blocks L-type calcium channels

Answer 27

TRUE

Question 28

True or False about verapamil. It increases heart rate

Answer 28

FALSE

Question 29

True or False about verapamil. It relaxes coronary artery smooth muscle

Answer 29

TRUE

Question 30

True or False about verapamil. It depresses cardiac contractility

Answer 30

TRUE

Question 31

Unwanted effects of clonidine

Answer 31

Sedative and hypnotic effects

Question 32

The reason of beta-blockers administration for hypertension treatment is

Answer 32

Decreasing of heart work

Question 33

An endogenous vasoconstrictor that can stimulate aldosterone release from suprarenal glands

Answer 33

Angiotensin II

Question 34

The group of antihypertensive drugs which diminishes the metabolism of bradykinin

Answer 34

Angiotensin-converting enzyme inhibitors

Question 35

Hydralazine (a vasodilator) can produce

Answer 35

Tachycardia, lupus erhythromatosis

Question 36

Vasodilator which releases NO

Answer 36

Sodium nitroprusside

Question 37

The reason of diuretics administration for hypertension treatment is

Answer 37

Diminishing of blood volume and amount of Na+ ions in the vessels endothelium

Question 38

Diuretic agent – aldosterone antagonist

Answer 38

Spironolactone

Question 39

Diuretic agent having a potent and rapid effect

Answer 39

Furosemide