AGENTS, CONTROLLING THE FUNCTIONS OF THE CENTRAL NERVOUS SYSTEM - Non-narcotic analgesics Flashcards
Non-narcotic analgesics are mainly effective against pain associated with
Inflammation or tissue damage
Non-narcotic agents cause
Antipyretic effect
Non-narcotic analgesics are
- Paracetamol
- Acetylsalicylic acid
- Ketorolac
Non-narcotic analgesics are not
Butorphanol
Select the non-narcotic drug, which is a paraaminophenol derivative
Paracetamol
Which of the following non-narcotic agents is salicylic acid derivative?
Aspirin
Tick pirazolone derivative
Analgin
Which non-narcotic agents inhibits mainly cyclooxygenase (COX) in CNS?
Paracetamol
Most of non-narcotic analgetics have
- Anti-inflammatory effect
- Analgesic effect
- Antipyretic effect
Indicate the non-narcotic analgesic, which lacks an anti-inflammatory effect
Paracetamol
True or False about aspirin. It inhibits mainly peripheral COX
TRUE
True or False about aspirin. It does not have an anti-inflammatory effect
FALSE
True or False about aspirin. It inhibits platelet aggregation.
TRUE
True or False about aspirin. It stimulates respiration by a direct action on the respiratory center
TRUE
For which conditions could aspirin be used prophylactically?
Thromboembolism
All of the following are undesirable effects of aspirin
- Gastritis with focal erosions
- Bleeding due to a decrease of platelet aggregation
- Reversible renal insufficiency
Is not a Undesirable effects of aspirin
Tolerance and physical addiction
Characteristic findinds of salicylism include
- Headache, mental confusion and drowsiness
- Tinnitus and difficulty in hearing
- Hyperthermia, sweating, thirst, hyperventilation, vomiting and diarrhea
Analgin usefulness is limited by
Agranulocytosis
Methemoglobinemia is possible adverse effect of
Paracetamol
True or False for ketorolac. It inhibits COX
TRUE
True or False for ketorolac. It is as effective as morphine for a short-term relief from moderate to severe pain
TRUE
True or False for ketorolac. It has a high potential for physical dependence and abuse
FALSE
True or False for ketorolac. It does not produce respiratory depression
TRUE
Indicate the nonopioid agent of central effect with analgesic activity
Clopheline
Select the antiseizure drug with an analgesic component of effect
Carbamazepine
Which nonopioid agents is an antidepressant with analgesic activity?
Amitriptyline
Tick mixed (opioid/non-opioid) agent
Tramadol