AGENTS, CONTROLLING THE FUNCTIONS OF THE CENTRAL NERVOUS SYSTEM - Non-narcotic analgesics Flashcards

1
Q

Non-narcotic analgesics are mainly effective against pain associated with

A

Inflammation or tissue damage

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2
Q

Non-narcotic agents cause

A

Antipyretic effect

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3
Q

Non-narcotic analgesics are

A
  • Paracetamol
  • Acetylsalicylic acid
  • Ketorolac
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4
Q

Non-narcotic analgesics are not

A

Butorphanol

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5
Q

Select the non-narcotic drug, which is a paraaminophenol derivative

A

Paracetamol

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6
Q

Which of the following non-narcotic agents is salicylic acid derivative?

A

Aspirin

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7
Q

Tick pirazolone derivative

A

Analgin

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8
Q

Which non-narcotic agents inhibits mainly cyclooxygenase (COX) in CNS?

A

Paracetamol

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9
Q

Most of non-narcotic analgetics have

A
  • Anti-inflammatory effect
  • Analgesic effect
  • Antipyretic effect
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10
Q

Indicate the non-narcotic analgesic, which lacks an anti-inflammatory effect

A

Paracetamol

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11
Q

True or False about aspirin. It inhibits mainly peripheral COX

A

TRUE

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12
Q

True or False about aspirin. It does not have an anti-inflammatory effect

A

FALSE

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13
Q

True or False about aspirin. It inhibits platelet aggregation.

A

TRUE

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14
Q

True or False about aspirin. It stimulates respiration by a direct action on the respiratory center

A

TRUE

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15
Q

For which conditions could aspirin be used prophylactically?

A

Thromboembolism

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16
Q

All of the following are undesirable effects of aspirin

A
  • Gastritis with focal erosions
  • Bleeding due to a decrease of platelet aggregation
  • Reversible renal insufficiency
17
Q

Is not a Undesirable effects of aspirin

A

Tolerance and physical addiction

18
Q

Characteristic findinds of salicylism include

A
  • Headache, mental confusion and drowsiness
  • Tinnitus and difficulty in hearing
  • Hyperthermia, sweating, thirst, hyperventilation, vomiting and diarrhea
19
Q

Analgin usefulness is limited by

A

Agranulocytosis

20
Q

Methemoglobinemia is possible adverse effect of

A

Paracetamol

21
Q

True or False for ketorolac. It inhibits COX

A

TRUE

22
Q

True or False for ketorolac. It is as effective as morphine for a short-term relief from moderate to severe pain

A

TRUE

23
Q

True or False for ketorolac. It has a high potential for physical dependence and abuse

A

FALSE

24
Q

True or False for ketorolac. It does not produce respiratory depression

A

TRUE

25
Q

Indicate the nonopioid agent of central effect with analgesic activity

A

Clopheline

26
Q

Select the antiseizure drug with an analgesic component of effect

A

Carbamazepine

27
Q

Which nonopioid agents is an antidepressant with analgesic activity?

A

Amitriptyline

28
Q

Tick mixed (opioid/non-opioid) agent

A

Tramadol