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Dental Physiology > Lec 7 - Synaptic Integration > Flashcards

Lec 7 - Synaptic Integration Flashcards

1
Q

ap remains constant throughout its duration so it is blank

A

electrotonic

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2
Q

trigger zone has the blank threshold

A

lowest

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3
Q

spatial summation changes the blank of the stimulus

A

intensity

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4
Q

epsp in motor neuron is caused by blank

A

glutamate

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5
Q

temporal summation changes the blank of the stimulus

A

frequency

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6
Q

increased frequency and temporal summation will result in calcium blank

A

facilitation

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7
Q

most inhibitory synapses are at dendritic shafts or the cell body nearest to the blank

A

trigger zone

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8
Q

presynaptic inhibition acts at blank synapses and decreases amount of blank release

A

axo axonic, nt

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9
Q

presynaptic inhibition functions to blank meaningless information

A

filter out (habituation)

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10
Q

mechanisms that accound for decreased quantal released and is PRESYNAPTIC

A

gabaB

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11
Q

these cells fine tunes muscle control by inhibiting weakly excited motor neurons and decreasing firing rate of strongly excited motor neurons

A

renshaw cell

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12
Q

blank receptors can modulate things

A

muscarinic

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13
Q

this is a neuropeptide released from unmyelinated pain fibers that causes burning pain sensation

A

substance p

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14
Q

this neuropeptide produces opioid like action that dulls pain perception

A

enkephalin

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15
Q

transmitter action is terminated by glial blank and axon terminal blank

A

uptake, reuptake

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16
Q

neuromodulators may modify these conductances via 2nd messengers

A

K+, Ca+

17
Q

dopamine and norepinephrine are the only nt that only activate these receptors

A

muscarinic receptors

18
Q

phosphoinositol system has the blank nt

A

Ach —muscarinic,gq, plc – ip3, dag, pkc, ca

19
Q

cAMP system has the blank nt

A

dopamine— dopamine receptor, gs/gi, adenylyl cyclase— cAMP, PKA

20
Q

2nd messenger yields significant blank of the extracellular signal

A

amplification

21
Q

beta adrenergic makes blank

A

Gs

22
Q

alpha adrenergic makes blank

A

Gi

23
Q

phospholipase C yields blank second messengers

A

2

24
Q

protein kinases blank signal transduction pathways

A

activate

25
Q

protein phosphatases blank the action of protein kinases

A

terminate

26
Q

only way to deactivate CaMKII

A

dephosphorylation by protein phosphatase

27
Q

extracellular to intracellular calcium ratio

A

10,000

28
Q

short term reg of cytosolic calcium

A

uptake

29
Q

long term reg of cytosolic calcium

A

extrude

30
Q

cGMP opens cation channels in blank receptors

A

photo

31
Q

cAMP opens cation channels in blank receptors

A

olfactory

32
Q

activation of CaMKII regulates the number of blank in the postsynaptic spine

A

AMPAR

33
Q

AMPAR, NMDAR, CaMKII are all involved in blank

A

LTP

Dental Physiology (60 decks)

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