Lec 7-6 - Ca Phosphate Homeostasis

Question 1

intracellular function of calcium

Answer 1

contraction, motility, secretion, growth, nerve function

Question 2

extracellular function of calcium

Answer 2

cell adhesion, aggregation of platelets, membrane integrity, blood coagulation

Question 3

phosphate functions

Answer 3

buffer, energy exchange, membranes, activate/inactivate enzymes

Question 4

most calcium and phosphate is here

Answer 4

bone

Question 5

the calcium and phosphate in the extracellular fluid are blank

Answer 5

regulated

Question 6

the calcium and phosphate in the intracellular fluid are blank

Answer 6

sequestered

Question 7

absorption of calcium and phosphate is done here

Answer 7

gut

Question 8

most calcium is absorbed here

Answer 8

duodenum

Question 9

most phosphate is absorbed here and is linear with diet.. not saturable like calcium absorption

Answer 9

jejunum

Question 10

the reabsorption and excretion of calcium and phosphate happen here

Answer 10

kidney

Question 11

phosphate reabsorption is blank dependent

Answer 11

sodium

Question 12

parathyroid hormone is made in blank cells of parathyroid gland

Answer 12

chief

Question 13

PTH is secreted when plasma calcium levels are blank in order to blank calcium reabsorption and blank phosphate reabsorption

Answer 13

low, increase, decrease

Question 14

calcitonin is made in blank cells of the thyroid gland

Answer 14

parafollicular

Question 15

calcitonin is secreted when plasma calcium levels are blank in order to blank calcium and phosphate secretion

Answer 15

high, decrease,

Question 16

vitamin d is made here

Answer 16

skin, liver, kidney

Question 17

low plasma phosphate increases the formation of this kind of vitamin D

Answer 17

1,25

Question 18

high plasma phosphate increases formation of this kind of vitamin D

Answer 18

24,25

Question 19

1,25 vitamin D causes blank of calcium and phosphate absorption

Answer 19

increase

Question 20

action of 1,25 vitamin D is inhibited by blank

Answer 20

glucocorticoids

Question 21

these cells are inactive osteoblasts that are connected to osteocytes via gap junctions and separate bone fluid from plasma

Answer 21

surface cells

Question 22

large multinucleated cells that do bone resorption via acid hydrolases

Answer 22

osteoclasts

Question 23

PTH and vitamin D blank bone formation and there are receptors on blank and blank

Answer 23

increases, osteocytes/osteoblasts

Question 24

calcitonin causes blank bone formation and there are receptors on blank

Answer 24

decreases, osteoclasts

Question 25

stimulating osteoblasts indirectly stimulates blank for remodeling

Answer 25

osteoclasts

Question 26

inhibiting osteoclasts indirectly inhibits blank for bone formation

Answer 26

calcitonin

Question 27

glucocorticoids decrease bone blank which can lead to blank

Answer 27

formation/degradation, osteoporosis

Question 28

both testosterone and estradiol help maintain blank

Answer 28

bone mass