Lec 5 - Synaptic Transmission

Question 1

Type of space between electrical synapse

Answer 1

Gap junction

Question 2

Type of space between chemical synapse

Answer 2

Synaptic cleft

Question 3

Electrical gap junctions have only blank signals

Answer 3

Excitatory

Question 4

Chemical signals can be either blank or blank

Answer 4

Excitatory, inhibitory

Question 5

Channels involved in chemical synapse

Answer 5

Ligand gated

Question 6

Synapse between neuron and skeletal muscle

Answer 6

Nmj

Question 7

Large size of nmj ensure high transmission blank

Answer 7

Reliability

Question 8

Nt at nmj

Answer 8

Ach

Question 9

Extracellular matrix of nmj contains blank

Answer 9

AchE

Question 10

This is what has the Ach receptors

Answer 10

Postsynaptic density

Question 11

Chemical transmission has a blank so it is slower than electrical

Answer 11

Synaptic delay

Question 12

1 nerve action potential releases 1 blank per active zone which generates a muscle action potential

Answer 12

Quantum

Question 13

End plate potential is due to blank

Answer 13

Ach receptors

Question 14

End plate potential at rest is blank

Answer 14

-90 mV

Question 15

When Ach receptors are activated, there is blank entry in the end plate

Answer 15

Sodium

Question 16

There is no blank at the peak of the end plate potential

Answer 16

Current

Question 17

End plate potential always makes a blank

Answer 17

Ap

Question 18

Curare is an AchR blank which makes it blank to have a MAP

Answer 18

Antagonist, harder

Question 19

End plate potential is always blank

Answer 19

Excitatory

Question 20

Inhibiting AchE blank transmitter action

Answer 20

Prolongs

Question 21

This is involved in the fission of the invaginated clathrin coated endocytosis pits

Answer 21

Dynamin

Question 22

These activate receptors

Answer 22

Agonists

Question 23

Curare is a blank antagonists

Answer 23

Nicotinic receptor

Question 24

Atropine is a blank receptor antagonist

Answer 24

Muscarinic

Question 25

Nicotinic ionotropic receptors have Ach being blank activated

Answer 25

Directly

Question 26

Metabotropic muscarinic receptors have Ach being blank activated

Answer 26

Indirectly

Question 27

Botulinum toxin blocks blank of vesicles

Answer 27

Exocytosis

Question 28

Alpha bungarotoxin is a venom that blocks blank

Answer 28

Ach

Question 29

Myasthenia gravis is an autoimmune blank disease that impairs nm transmission by destroying AchRs

Answer 29

Postsynaptic

Question 30

Lambert eaton myasthenic syndrome is an autoimmune blank disease that impairs nm transmission by destroying Calcium channels

Answer 30

Presynaptic

Question 31

Process by which neurons send signals to target cells

Answer 31

Synaptic transmission