Lec 2 Chemical and Electric Signals

Question 1

when a neuron is at a resting potential of -70 mV, neither potassium nor sodium is at blank

Answer 1

equilibrium? ok

Question 2

driving force generated by a concentration difference and applies to all charged and uncharged molecules

Answer 2

diffusive chemical

Question 3

driving force generated by a potential difference in an electrical field and only applies to charged particles

Answer 3

electrical

Question 4

answer of nernst equation gives us the blank

Answer 4

equilibrium potential

Question 5

g is aka

Answer 5

conductance

Question 6

conductance can increase due to these two thing

Answer 6

larger channel, more channels

Question 7

depolarization occurs via opening blank channels and closing blank channels

Answer 7

sodium, potassium

Question 8

shunting inhibition example

Answer 8

chloride channels being open keeps cell at -70 mV because that is its equilibrium potential

Question 9

equilibrium potential of sodium

Answer 9

+60

Question 10

equilibrium potential of potassium

Answer 10

-90

Question 11

three types of gated channels

Answer 11

voltage, ligand, mechanically

Question 12

sodium channel has blank domains that each have blank TM segments

Answer 12

four, six

Question 13

potassium channel has one blank TM peptide

Answer 13

6

Question 14

unique 6 TM channel that can detect environmental clues

Answer 14

TRP

Question 15

equilibrium potential for the ion is aka the blank

Answer 15

nernst potential

Question 16

Loop of 6 transmembrane channel that is the selectivity filter

Answer 16

P loop

Question 17

ENaC is an epithelium sodium channel is always blank

Answer 17

Open

Question 18

Receptors that bind ligand and rapidly activate channel because channel is part of the receptor

Answer 18

Ionotropic

Question 19

Receptors that bind ligand slowly and activate a g protein

Answer 19

Metabotropic receptors (GPCR)

Question 20

Excitatory ionotropic receptors

Answer 20

Glutamate, Ach

Question 21

Inhibitory ionotropic receptors

Answer 21

Gaba, glycine

Question 22

G protein coupled receptor does not have a blank

Answer 22

Channel