Lec 2/3-7 - Saliva and Stomach Flashcards

1
Q

Mucus, HCO3, and antibacterial enzymes are all blank functions of saliva

A

Protects

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2
Q

Alpha amylase, lingual lipase are two blank functions of saliva

A

Digestive

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3
Q

Salivary glands are blank

A

Exocrine

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4
Q

We make almost this much saliva per day

A

1 L

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5
Q

Saliva is always blank compared to interstitial fluid (300 mOsmo/L)

A

Hypotonic (75-200 mOsm/L)

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6
Q

These cells modify the acinar fluid as it flows through the ducts

A

Duct cells

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7
Q

Slower flow through acinus of sodium chloride allows these to transport sodium and increase concentration of sodium in blank

A

ENAC, saliva

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8
Q

understand the mechanism of saliva movement slides

A

Ok

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9
Q

Cholinergic stimulation results in blank volume of saliva

A

High

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10
Q

Beta adrenergic stimulation of saliva causes blank volume

A

Decreased

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11
Q

Antibodies to salivary and lacrimal glands autoimmune disease

A

Sjogren syndrome

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12
Q

Sjogren syndrome has expression of blank in the ducts being lost

A

Cl- HCO3- exchanger

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13
Q

Duct structure responsible for saliva secretion

A

Salivon

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14
Q

esophagus doesnt have much blank but blank is very important here

A

secretion, motility

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15
Q

this gastric juice made by the stomach is essential for vitamin B12 absorption

A

intrinsic factor

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16
Q

function of the acid in the stomach is blank and activates blank from blank

A

killing bacteria, pepsin, pepsinogen

17
Q

secreted volume of acid of the stomach per day (water)

A

2-3 Liters

18
Q

cells of the stomach that make HCl, KC, intrinsic factor

A

oxyntic parietal cells

19
Q

cells of the stomach that make pepsinogen

A

peptic chief cells

20
Q

these stimulate increased acidity by increasing hydrogen ions in the stomach

A

histamine and eating a meal

21
Q

this decreases in the stomach due to the increased volume during a meal or from histamine because of large water volume diluting the sodium concentration

A

sodium

22
Q

stimulated parietal cell has a huge jump in blank when stimulated

A

surface area

23
Q

gi tract lumen is electrically blank with respect to the plasma

A

negative

24
Q

g cells in the antrum make this

A

gastrin

25
Q

three things that stimulate acid secretion by parietal cells

A

vagal stimulation, gastrin, histamine

26
Q

unique histamine receptor in the stomach that can be targeted by drugs to reduce acid secretion

A

H2

27
Q

atropine blocks this part of acid secretion

A

vagal stimulation

28
Q

cimetidine blocks this part of acid secretion

A

histamine

29
Q

omeprazole blocks acid secretion into the lumen by blocking blank

A

sodium potassium pump

30
Q

bacteria responsible for most gastric ulcers

A

helicobacter pylori