Lec 2/3-7 - Saliva and Stomach Flashcards
Mucus, HCO3, and antibacterial enzymes are all blank functions of saliva
Protects
Alpha amylase, lingual lipase are two blank functions of saliva
Digestive
Salivary glands are blank
Exocrine
We make almost this much saliva per day
1 L
Saliva is always blank compared to interstitial fluid (300 mOsmo/L)
Hypotonic (75-200 mOsm/L)
These cells modify the acinar fluid as it flows through the ducts
Duct cells
Slower flow through acinus of sodium chloride allows these to transport sodium and increase concentration of sodium in blank
ENAC, saliva
understand the mechanism of saliva movement slides
Ok
Cholinergic stimulation results in blank volume of saliva
High
Beta adrenergic stimulation of saliva causes blank volume
Decreased
Antibodies to salivary and lacrimal glands autoimmune disease
Sjogren syndrome
Sjogren syndrome has expression of blank in the ducts being lost
Cl- HCO3- exchanger
Duct structure responsible for saliva secretion
Salivon
esophagus doesnt have much blank but blank is very important here
secretion, motility
this gastric juice made by the stomach is essential for vitamin B12 absorption
intrinsic factor
function of the acid in the stomach is blank and activates blank from blank
killing bacteria, pepsin, pepsinogen
secreted volume of acid of the stomach per day (water)
2-3 Liters
cells of the stomach that make HCl, KC, intrinsic factor
oxyntic parietal cells
cells of the stomach that make pepsinogen
peptic chief cells
these stimulate increased acidity by increasing hydrogen ions in the stomach
histamine and eating a meal
this decreases in the stomach due to the increased volume during a meal or from histamine because of large water volume diluting the sodium concentration
sodium
stimulated parietal cell has a huge jump in blank when stimulated
surface area
gi tract lumen is electrically blank with respect to the plasma
negative
g cells in the antrum make this
gastrin
three things that stimulate acid secretion by parietal cells
vagal stimulation, gastrin, histamine
unique histamine receptor in the stomach that can be targeted by drugs to reduce acid secretion
H2
atropine blocks this part of acid secretion
vagal stimulation
cimetidine blocks this part of acid secretion
histamine
omeprazole blocks acid secretion into the lumen by blocking blank
sodium potassium pump
bacteria responsible for most gastric ulcers
helicobacter pylori
