Lec 1 Flashcards

1
Q

2 things that cant go through membrane

A

large uncharged polar molecules, charged ions

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2
Q

2 large uncharged molecules

A

glucose, sucrose

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3
Q

proteins that are not open simultaneously to both the inside and outside the cell

A

carrier

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4
Q

proteins that are either all the way open or all the way close to both sides

A

channel

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5
Q

carrier proteins can be blank or blank transport

A

primary active, secondary active

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6
Q

carriers move molecules blank concentration gradient

A

against

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7
Q

secondary active transport uses blank energy

A

potential

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8
Q

sodium potassium pump has sodium and potassium going blank their conc gradients… 3 sodium go blank and 2 potassium go blank

A

against, out, in

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9
Q

phosphorylation of atpase changes the blank which changes the blank from the outside to the inside

A

conformation, open side

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10
Q

extrusion of blank provides potential energy for most secondary active transport

A

sodium

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11
Q

sodium potassium pump uses blank of the energy used by the body and blank percent of the energy used by the brain

A

25, 70

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12
Q

sodium potassium pump is blank which means it is contributing to the small amount to the resting blank membrane potential

A

negative

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13
Q

steps of secondary active transport

A

sodium binds to carrier, sodium binding creates a site for glucose in carrier, glucose binding changes carrier conformation, sodium released into cytosol and glucose follows

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14
Q

protein that does secondary active transport of glucose

A

sglt

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15
Q

inhibiting the sodium potassium pump would increase the concentration of blank in the cell due to decreased function of blank

A

calcium, sodium calcium exchanger

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16
Q

na ca exchanger moves blank in and blank out

A

sodium, calcium

17
Q

the equilibrium potential is when the blank gradient exactly opposes the blank gradient

A

electrical, concentration

18
Q

cells normally maintain an internal voltage of about blank

A

-70 mV

19
Q

charge =

A

ions

20
Q

current =

A

ions/sec

21
Q

energy to move charge

A

voltage (potential)

22
Q

ease of moving charge across membrane

A

conductance (1/resistance)

23
Q

excitation makes voltage more blank

A

positive

24
Q

inhibition makes voltage more blank

A

negative

25
Q

depolarization makes cell more blank

A

positive

26
Q

hyperpolarization makes cell more blank

A

negative

27
Q

two key events that are initiated by depolarization

A

producing action potential, releasing nt

28
Q

2 things that are membrane permeable

A

hydrophobic molecules, small uncharged polar molecules