Lec 3-6 - Thyroid Flashcards

1
Q

hormone that enables other hormones to work normally

A

permissive hormone

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2
Q

cells in the thyroid that actually make thyroid hormone

A

follicular cells

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3
Q

where thyroid stores thyroid hormone

A

colloid inside thyroid itself

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4
Q

t4 is aka

A

thyroxine

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5
Q

t4 is the blank

A

prohormone

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6
Q

t3 actually blank

A

does the most activity

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7
Q

t3 is aka

A

triidothyronine

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8
Q

enzyme required to put iodine on to thyroglobulin to make t3 and t4

A

thyroid peroxidase

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9
Q

steps in making t3 and t4

A

iodine comes into follicular cell, thyroid peroxidase puts iodine on thyroglobulin and stores in colloid, long chain goes back into follicular cell and is snipped into t1,t2,t3,t4; we use the t3 and t4 and recycle t1 and t2

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10
Q

not enough iodine causes blank

A

no negative feedback so amount of thyroid stimulating hormone in colloid increases and thyroid gets huge because t3 and t4 doesnt get released from the colloid

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11
Q

does t3 or t4 actually do the negative feedback on thyrotrophs

A

t3

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12
Q

transport of thyroid hormone is via

A

thyroxine binding globulin, albumin (main one)

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13
Q

thyroid hormone causes growth of blank by setting the stage for other hormones

A

skeletal system, teeth, central nervous system

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14
Q

thyroid hormone causes increased metabolism by using more blank by breaking down more lipids and proteins

A

oxygen

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15
Q

therefore, hyperthyroidism causes blank which leads to feeling blank all the time and blank heart rate

A

catabolism, hot, increased

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16
Q

hyperthyroidism is aka blank

A

grave’s disease

17
Q

hypothyroidism is aka blank

A

hashimoto’s disease