Lec 3-6 - Thyroid Flashcards
hormone that enables other hormones to work normally
permissive hormone
cells in the thyroid that actually make thyroid hormone
follicular cells
where thyroid stores thyroid hormone
colloid inside thyroid itself
t4 is aka
thyroxine
t4 is the blank
prohormone
t3 actually blank
does the most activity
t3 is aka
triidothyronine
enzyme required to put iodine on to thyroglobulin to make t3 and t4
thyroid peroxidase
steps in making t3 and t4
iodine comes into follicular cell, thyroid peroxidase puts iodine on thyroglobulin and stores in colloid, long chain goes back into follicular cell and is snipped into t1,t2,t3,t4; we use the t3 and t4 and recycle t1 and t2
not enough iodine causes blank
no negative feedback so amount of thyroid stimulating hormone in colloid increases and thyroid gets huge because t3 and t4 doesnt get released from the colloid
does t3 or t4 actually do the negative feedback on thyrotrophs
t3
transport of thyroid hormone is via
thyroxine binding globulin, albumin (main one)
thyroid hormone causes growth of blank by setting the stage for other hormones
skeletal system, teeth, central nervous system
thyroid hormone causes increased metabolism by using more blank by breaking down more lipids and proteins
oxygen
therefore, hyperthyroidism causes blank which leads to feeling blank all the time and blank heart rate
catabolism, hot, increased