Lec 2-4 - Renal Flashcards
A conceptual measure that is used for the calculation of GFR in mL/min
Clearance
Clearance is the blank of plasma that the kidneys can clear of a substance per minute
Volume
How to calculate clearance calculation will be on test
Ok
Different substances have different blank values
Clearance
Some substances do not get blank at all
Filtered
Any plasma component in the urine will have a blank clearance value
Non zero
Clearance value that is completely removed from plasma
Maximum clearance value
Plasma is cleared here and here
Peritubular capillaries (85%), glomerulus (15%)
Clearance will equal blank if it is totally cleared
Renal plasma flow
Renal artery input =
Renal vein output + ureter output
Clearance only equals GFR in blank cases
Special
If the kidneys arent working, there will be a build up of blank in the blood
Creatinine
Healthy neurons will blank for failing nephrons so GFR will actually blank the extent of nephron loss
Compensate, underestimate
Force exerted by plasma fluid on capillary walls
Hydrostatic pressure
Pressure that acts against hydrostatic pressure
Osmotic (oncotic) pressure
Ultrafiltration pressure formula
Puf = Pgc - Pbs - (Pi)gc
Gfr formula
Puf x Kf
Kf basically is the blank of the capillaries
Permeability
Need to go through these slides
Ok
Renal blood flow remains blank so it is pretty much independent of blood pressure values
Constant
Mechanism responsible for maintaining the constant blood flow in the kidney
Myogenic
An elevated gfr causes blank to enter the nephron
Too much fluid
Atp bind to cellular receptors in the blank
Juxtaglomerular apparatus
Best indicator of renal function that is the functional measure of the sum of all the nephrons
Glomerular filtration rate
