Immunohematology- Components Flashcards
1
Q
- A male cancer patient with a hemoglobin of 6 g/dL
was admitted to the hospital with acute abdominal
pain. Small bowel resection was indicated, but the
attending physician wanted to raise the patient’s
hemoglobin to 12 g/dL before surgery. How many
units of RBCs would most likely be required to
accomplish this?
A. 2
B. 3
C. 6
D. 8
A
C. 6
2
Q
- Which of the following is not a viable method for
removing leukocytes from red blood cells?
A. Prestorage filtration
B. Bedside filtration
C. Poststorage filtration
D. Buffy coat removal
A
D. Buffy coat remova
3
Q
- Four units of packed RBCs were brought to the
nurses’ station at 10:20 a.m. Two units were
transfused immediately, and 1 unit was transfused
at 10:40 a.m. The remaining unit was returned to
the blood bank at 11:00 a.m. The units were not
refrigerated after leaving the blood bank. What
problem(s) is (are) present in this situation?
A. The only problem is with the returned unit; the
30-minute limit has expired and the unit cannot
be used
B. The unit should not have been transfused at
10:40 a.m. because the time limit had expired;
this unit and the remaining unit should have
been returned to the blood bank
C. The returned unit may be held for this patient
for 48 hours but cannot be used for another
patient
D. No problems; all actions were performed within
the allowable time limits
A
A. The only problem is with the returned unit; the
30-minute limit has expired and the unit cannot
be used
4
Q
- A unit of whole blood is collected at 10:00 a.m.
and stored at 20°C–24°C. What is the last hour
platelet concentrates may be made from this unit?
A. 4:00 p.m.
B. 6:00 p.m.
C. 7:00 p.m.
D. 8:00 p.m
A
B. 6:00 p.m.
5
Q
- Which of the following is acceptable according to
AABB standards?
A. Rejuvenated RBCs may be made within 3 days
of outdate and transfused or frozen within
24 hours of rejuvenation
B. Frozen RBCs must be prepared within 30 minutes
of collection and may be used within 10 years
C. Irradiated RBCs must be treated within 8 hours
of collection and transfused within 6 hours
D. Leukocyte-reduced RBCs must be prepared
within 6 hours of collection and transfused
within 6 hours of preparation
A
A. Rejuvenated RBCs may be made within 3 days
of outdate and transfused or frozen within
24 hours of rejuvenation
6
Q
- Which of the following is true regarding apheresis
platelets?
A. The minimum platelet count must be 3.0 × 1011,
pH must be ≥6.0
B. The minimum platelet count must be 3.0 × 1010,
pH must be ≤6.2
C. The minimum platelet count must be 3.0 × 1011,
pH must be ≥6.2
D. The minimum platelet count must be 5.5 × 1010,
pH must be ≤6.0
A
C. The minimum platelet count must be 3.0 × 1011,
pH must be ≥6.2
7
Q
- What is the component of choice for a patient
with chronic granulomatous disease (CGD)?
A. FFP
B. Granulocytes
C. Cryoprecipitate
D. RBCs
A
B. Granulocytes
8
Q
- What method can be employed to detect bacteria
in random donor platelets?
A. pH
B. Glucose
C. Pan genera detection (PGD) assay
D. Gram stain
A
C. Pan genera detection (PGD) assay
9
Q
- All of the following statements regarding FFP are
true, except:
A. FFP must be prepared within 24 hours of
collection
B. After thawing, FFP must be transfused within
24 hours
C. Storage temperature for FFP with a 1-year shelf
life is ≤−18°C
D. When thawed, FFP must be stored between
1°C–6°C
A
A. FFP must be prepared within 24 hours of
collection
10
Q
- What may be done to RBCs before transfusion to
a patient with cold agglutinin disease in order to
reduce the possibility of a transfusion reaction?
A. Irradiate to prevent graft-versus-host-disease
(GVHD)
B. Wash with 0.9% percent saline
C. Warm to 37°C with a blood warmer
D. Transport so that temperature is maintained at
20°C–24°C
A
C. Warm to 37°C with a blood warmer
11
Q
- A unit of packed RBCs is split using the open
system. One of the half units is used. What may be
done with the second half unit?
A. Must be issued within 24 hours
B. Must be issued within 48 hours
C. Must be irradiated
D. Must retain the original expiration date
A
A. Must be issued within 24 hours
12
Q
- What should be done if a noticeable clot is found
in an RBC unit?
A. Issue the unit; the blood will be filtered
B. Issue the unit; note the presence of a clot on the
release form
C. Filter the unit in the blood bank before issue
D. Do not issue the unit
A
D. Do not issue the unit
13
Q
- Cryoprecipitate may be used to treat all of the
following, except:
A. von Willebrand’s disease
B. Hypofibrinogenemia
C. Idiopathic thrombocytopenic purpura (ITP)
D. Factor XIII deficiency
A
C. Idiopathic thrombocytopenic purpura (ITP)
14
Q
- SITUATION: A transplant patient may receive
only type A or AB platelets. There are only type O
apheresis platelets available. What devices may be
used to deplete the incompatible plasma and
replace with sterile saline?
A. Cytospin/irradiator
B. Water bath/centrifuge
C. Centrifuge/sterile connecting device
D. Cell washer/heat sealer
A
C. Centrifuge/sterile connecting device
15
Q
- What component(s) is (are) indicated for patients
who have anti-IgA antibodies?
A. Whole blood
B. Packed RBCs
C. Washed or deglycerolized RBCs
D. Granulocytes
A
C. Washed or deglycerolized RBCs
16
Q
- FFP can be transfused without regard for:
A. ABO type
B. Rh type
C. Antibody in product
D. All of these options
A
B. Rh type
17
Q
- All of the following are true regarding washed
RBCs, except:
A. RBCs are washed with 1–2 L of normal saline
B. Volume is 180 mL
C. Shelf life is extended
D. Leukocytes are removed
A
C. Shelf life is extended
18
Q
- What is a special condition for the storage of
platelets?
A. Room temperature, 20°C–24°C
B. No other components may be stored with
platelets
C. Platelets must be stored upright in separate
containers
D. Platelets require constant agitation at 20°C–24°C
A
D. Platelets require constant agitation at 20°C–24°C
19
Q
- Transfusion of an irradiated product is indicated
in all of the following conditions except:
A. Exchange transfusion
B. Bone marrow transplant
C. Severe combined immunodeficiency syndrome
(SCIDS)
D. Warm autoimmune hemolytic anemia (WAIHA)
A
D. Warm autoimmune hemolytic anemia (WAIHA)
20
Q
- What percentage of red cells must be retained in
leukocyte-reduced red cells?
A. 75%
B. 80%
C. 85%
D. 100%
A
C. 85%
21
Q
- Which of the following is true regarding
granulocyte concentrates?
A. The product must contain a maximum of
1.0 × 1010 granulocytes
B. The pH must be 6.0
C. The product must be crossmatched
D. The product must be irradiated
A
C. The product must be crossmatched
22
Q
- What course of action should be taken if a medical
laboratory scientist inadvertently irradiates a unit
of red cells twice?
A. Issue the unit
B. Discard the unit
C. Change the expiration date; then issue the unit
D. Note on the irradiation sticker that the unit was
irradiated twice and issue
A
B. Discard the unit
23
Q
- What components(s) may be shipped together
with FFP?
A. Frozen RBCs and cryoprecipitate
B. Platelets
C. Packed RBCs and granulocytes
D. Double red cell
A
A. Frozen RBCs and cryoprecipitate
24
Q
- A blood supplier ships 3 units of pooled
cryoprecipitate. Each pool consists of 5 units of
cryoprecipitate. If one unit is thawed at 5:00 p.m.,
when must it be dispensed from the blood bank?
A. Before 9:00 p.m.
B. Before 11:00 p.m.
C. Before 12:00 a.m.
D. Before 5:00 p.m. the next day
A
A. Before 9:00 p.m.
25
Q
- How does irradiation prevent transfusion
associated graft-versus-host disease (TA-GVHD)?
A. Gamma rays and x-rays destroy the lymphocytes’
ability to divide
B. X-rays cause lysis of the lymphocytes
C. Gamma rays enhance lymphocyte reactivity
D. Ultraviolet radiation induces apoptosis of
lymphocytes
A
A. Gamma rays and x-rays destroy the lymphocytes’
ability to divide
26
Q
- Which component has the longest expiration date?
A. Cryoprecipitate
B. FFP
C. Frozen RBCs
D. Platelet concentrates
A
C. Frozen RBCs
27
Q
- All of the following are advantages of using singledonor platelets as opposed to random donor
platelets, except:
A. Less preparation time
B. Less antigen exposure for patients
C. May be HLA matched
D. No pooling is required
A
A. Less preparation time
28
Q
- What is the expiration of cryoprecipitate once
pooled?
A. 4 hours
B. 6 hours
C. 8 hours
D. 24 hours
A
A. 4 hours
29
Q
- What is the number of white blood cells permitted
in a unit of leukoreduced red cells?
A. <5 × 1010
B. <5 × 106
C. <8.3 × 105
D. <8.3 × 106
A
B. <5 × 106
30
Q
- SITUATION: A cancer patient recently developed
a severe infection. The patient’s hemoglobin is
8 g/dL owing to chemotherapy with a drug
known to cause bone marrow depression and
immunodeficiency. Which blood products are
indicated for this patient?
A. Liquid plasma and cryoprecipitate
B. Crossmatched platelets and washed RBCs
C. Factor IX concentrates and FFP
D. Irradiated RBCs, platelets, and granulocytes
A
D. Irradiated RBCs, platelets, and granulocytes
