Immuhematology- Rh Blood Group System Flashcards
1
Q
- A complete Rh typing for antigens C, c, D, E, and
e revealed negative results for C, D, and E. How is
the individual designated?
A. Rh positive
B. Rh negative
C. Positive for c and e
D. Impossible to determine
A
B. Rh negative
2
Q
- How is an individual with genotype Dce/dce
classified?
A. Rh positive
B. Rh negative
C. Rhnull
D. Total Rh
A
A. Rh positive
3
Q
- If a patient has a positive direct antiglobulin test,
should you perform a weak D test on the cells?
A. No, the cells are already coated with antibody
B. No, the cells are Rhnull
C. Yes, the immunoglobulin will not interfere with
the test
D. Yes, Rh reagents are enhanced in protein media
A
A. No, the cells are already coated with antibody
4
Q
- Which donor unit is selected for a recipient with
anti-c?
A. r´r
B. R0R1
C. R2r´
D. r´ry
A
D. r´ry
5
Q
- Which genotype usually shows the strongest
reaction with anti-D?
A. DCE/DCE
B. Dce/dCe
C. D–/D–
D. -CE/-ce
A
C. D–/D–
6
Q
- Why is testing for Rh antigens and antibodies
different from ABO testing?
A. ABO reactions are primarily due to IgM
antibodies and usually occur at room
temperature; Rh antibodies are IgG and
agglutination usually requires a 37°C incubation
and enhancement media
B. ABO antigens are attached to receptors on the
outside of the red cell and do not require any
special enhancement for testing; Rh antigens are
loosely attached to the red cell membrane and
require enhancement for detection
C. Both ABO and Rh antigens and antibodies have
similar structures, but Rh antibodies are
configured so that special techniques are needed
to facilitate binding to Rh antigens
D. There is no difference in ABO and Rh testing;
both may be conducted at room temperature
with no special enhancement needed for reaction
A
A. ABO reactions are primarily due to IgM
antibodies and usually occur at room
temperature; Rh antibodies are IgG and
agglutination usually requires a 37°C incubation
and enhancement media
7
Q
- Testing reveals a weak D that reacts 1+ after
indirect antiglobulin testing (IAT). How is this
result classified?
A. Rh-positive
B. Rh-negative, Du positive
C. Rh-negative
D. Rh-positive, Du positive
A
A. Rh-positive
8
Q
- What is one possible genotype for a patient who
develops anti-C antibody?
A. R1r
B. R1R1
C. r´r
D. rr
A
D. rr
9
Q
- A patient developed a combination of Rh
antibodies: anti-C, anti-E, and anti-D. Can
compatible blood be found for this patient?
A. It is almost impossible to find blood lacking the
C, E, and D antigens
B. rr blood could be used without causing a
problem
C. R0R0 may be used because it lacks all three
antigens
D. Although rare, ryr blood may be obtained from
close relatives of the patient
A
B. rr blood could be used without causing a
problem
10
Q
- A patient tests positive for weak D but also
appears to have anti-D in his serum. What may be
the problem?
A. Mixup of samples or testing error
B. Most weak D individuals make anti-D
C. The problem could be due to a disease state
D. A D mosaic may make antibodies to missing
antigen parts
A
D. A D mosaic may make antibodies to missing
antigen parts
11
Q
- Which offspring is not possible from a mother who
is R1R2 and a father who is R1r?
A. DcE/DcE
B. Dce/DCe
C. DcE/DCe
D. Dce/dce
A
A. DcE/DcE
12
Q
- Why is testing a pregnant woman for weak D not
required?
A. An Rh-negative fetus may yield false positive
results in a fetal maternal bleed
B. An Rh-positive fetus may yield false positive
results in a fetal maternal bleed
C. D antigen strength decreases during pregnancy
D. D antigen strength increases during pregnancy
A
B. An Rh-positive fetus may yield false positive
results in a fetal maternal bleed
13
Q
- What antibodies could an R1R1 make if exposed to
R2R2 blood?
A. Anti-e and anti-C
B. Anti-E and anti-c
C. Anti-E and anti-C
D. Anti-e and anti-c
A
B. Anti-E and anti-c
14
Q
- What does the genotype —/— represent in the
Rh system?
A. Rh negative
B. D mosaic
C. Rhnull
D. Total Rh
A
C. Rhnull
15
Q
- What techniques are necessary for weak D testing?
A. Saline + 22°C incubation
B. Albumin or LISS + 37°C incubation
C. Saline + 37°C incubation
D. 37°C incubation + IAT
A
D. 37°C incubation + IAT