Immuhematology- Rh Blood Group System Flashcards

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1
Q
  1. A complete Rh typing for antigens C, c, D, E, and
    e revealed negative results for C, D, and E. How is
    the individual designated?
    A. Rh positive
    B. Rh negative
    C. Positive for c and e
    D. Impossible to determine
A

B. Rh negative

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2
Q
  1. How is an individual with genotype Dce/dce
    classified?
    A. Rh positive
    B. Rh negative
    C. Rhnull
    D. Total Rh
A

A. Rh positive

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3
Q
  1. If a patient has a positive direct antiglobulin test,
    should you perform a weak D test on the cells?
    A. No, the cells are already coated with antibody
    B. No, the cells are Rhnull
    C. Yes, the immunoglobulin will not interfere with
    the test
    D. Yes, Rh reagents are enhanced in protein media
A

A. No, the cells are already coated with antibody

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4
Q
  1. Which donor unit is selected for a recipient with
    anti-c?
    A. r´r
    B. R0R1
    C. R2r´
    D. r´ry
A

D. r´ry

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5
Q
  1. Which genotype usually shows the strongest
    reaction with anti-D?
    A. DCE/DCE
    B. Dce/dCe
    C. D–/D–
    D. -CE/-ce
A

C. D–/D–

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6
Q
  1. Why is testing for Rh antigens and antibodies
    different from ABO testing?
    A. ABO reactions are primarily due to IgM
    antibodies and usually occur at room
    temperature; Rh antibodies are IgG and
    agglutination usually requires a 37°C incubation
    and enhancement media
    B. ABO antigens are attached to receptors on the
    outside of the red cell and do not require any
    special enhancement for testing; Rh antigens are
    loosely attached to the red cell membrane and
    require enhancement for detection
    C. Both ABO and Rh antigens and antibodies have
    similar structures, but Rh antibodies are
    configured so that special techniques are needed
    to facilitate binding to Rh antigens
    D. There is no difference in ABO and Rh testing;
    both may be conducted at room temperature
    with no special enhancement needed for reaction
A

A. ABO reactions are primarily due to IgM
antibodies and usually occur at room
temperature; Rh antibodies are IgG and
agglutination usually requires a 37°C incubation
and enhancement media

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7
Q
  1. Testing reveals a weak D that reacts 1+ after
    indirect antiglobulin testing (IAT). How is this
    result classified?
    A. Rh-positive
    B. Rh-negative, Du positive
    C. Rh-negative
    D. Rh-positive, Du positive
A

A. Rh-positive

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8
Q
  1. What is one possible genotype for a patient who
    develops anti-C antibody?
    A. R1r
    B. R1R1
    C. r´r
    D. rr
A

D. rr

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9
Q
  1. A patient developed a combination of Rh
    antibodies: anti-C, anti-E, and anti-D. Can
    compatible blood be found for this patient?
    A. It is almost impossible to find blood lacking the
    C, E, and D antigens
    B. rr blood could be used without causing a
    problem
    C. R0R0 may be used because it lacks all three
    antigens
    D. Although rare, ryr blood may be obtained from
    close relatives of the patient
A

B. rr blood could be used without causing a
problem

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10
Q
  1. A patient tests positive for weak D but also
    appears to have anti-D in his serum. What may be
    the problem?
    A. Mixup of samples or testing error
    B. Most weak D individuals make anti-D
    C. The problem could be due to a disease state
    D. A D mosaic may make antibodies to missing
    antigen parts
A

D. A D mosaic may make antibodies to missing
antigen parts

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11
Q
  1. Which offspring is not possible from a mother who
    is R1R2 and a father who is R1r?
    A. DcE/DcE
    B. Dce/DCe
    C. DcE/DCe
    D. Dce/dce
A

A. DcE/DcE

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12
Q
  1. Why is testing a pregnant woman for weak D not
    required?
    A. An Rh-negative fetus may yield false positive
    results in a fetal maternal bleed
    B. An Rh-positive fetus may yield false positive
    results in a fetal maternal bleed
    C. D antigen strength decreases during pregnancy
    D. D antigen strength increases during pregnancy
A

B. An Rh-positive fetus may yield false positive
results in a fetal maternal bleed

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13
Q
  1. What antibodies could an R1R1 make if exposed to
    R2R2 blood?
    A. Anti-e and anti-C
    B. Anti-E and anti-c
    C. Anti-E and anti-C
    D. Anti-e and anti-c
A

B. Anti-E and anti-c

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14
Q
  1. What does the genotype —/— represent in the
    Rh system?
    A. Rh negative
    B. D mosaic
    C. Rhnull
    D. Total Rh
A

C. Rhnull

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15
Q
  1. What techniques are necessary for weak D testing?
    A. Saline + 22°C incubation
    B. Albumin or LISS + 37°C incubation
    C. Saline + 37°C incubation
    D. 37°C incubation + IAT
A

D. 37°C incubation + IAT

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16
Q
  1. A patient types as AB and appears to be Rh
    positive on slide typing. What additional tests
    should be performed for tube typing?
    A. Rh negative control
    B. Direct antiglobulin test (DAT)
    C. Low-protein Rh antisera
    D. No additional testing is needed
A

A. Rh negative control

17
Q
  1. According to the Wiener nomenclature and/or
    genetic theory of Rh inheritance:
    A. There are three closely linked loci, each with a
    primary set of allelic genes
    B. The alleles are named R1, R2, R0, r, r´, r˝, Rz,
    and ry
    C. There are multiple alleles at a single complex
    locus that determine each Rh antigen
    D. The antigens are named D, C, E, c, and e
A

C. There are multiple alleles at a single complex
locus that determine each Rh antigen

18
Q
  1. The Wiener nomenclature for the E antigen is:
    A. hr´
    B. hrv´
    C. rh˝
    D. Rh0
A

C. rh˝

19
Q
  1. A physician orders 2 units of leukocyte-reduced
    red blood cells. The patient is a 55-year-old male
    with anemia. He types as an AB negative, and his
    antibody screen is negative. There is only 1 unit of
    AB negative in inventory. What is the next blood
    type that should be given?
    A. AB positive (patient is male)
    B. A negative
    C. B negative
    D. O negative
A

B. A negative

20
Q
  1. Which technology may report an Rh-weak D
    positive as Rh negative?
    A. Gel System
    B. Solid Phase
    C. Tube Testing
    D. None of these options
A

A. Gel System