Immunohematology- Compatibility Testing Flashcards
1
Q
- SITUATION: An emergency trauma patient
requires transfusion. Six units of blood are ordered
stat. There is no time to draw a patient sample.
O-negative blood is released. When will
compatibility testing be performed?
A. Compatibility testing must be performed before
blood is issued
B. Compatibility testing will be performed when a
patient sample is available
C. Compatibility testing may be performed
immediately using donor serum
D. Compatibility testing is not necessary when
blood is released in emergency situations
A
B. Compatibility testing will be performed when a
patient sample is available
2
Q
- How would autoantibodies affect compatibility
testing?
A. No effect
B. The DAT would be positive
C. ABO, Rh, antibody screen, and crossmatch may
show abnormal results
D. Results would depend on the specificity of
autoantibody
A
C. ABO, Rh, antibody screen, and crossmatch may
show abnormal results
3
Q
- An antibody screen is reactive at IAT phase of
testing using a three-cell screen and the
autocontrol is negative. What is a possible
explanation for these results?
A. A cold alloantibody
B. High-frequency alloantibody or a mixture of
alloantibodies
C. A warm autoantibody
D. A cold and warm alloantibody
A
B. High-frequency alloantibody or a mixture of
alloantibodies
4
Q
- What does a minor crossmatch consist of?
A. Recipient plasma and recipient red cells
B. Recipient plasma and donor red cells
C. Recipient red cells and donor plasma
D. Donor plasma and donor red cells
A
C. Recipient red cells and donor plasma
5
Q
- Can crossmatching be performed on October 14th
using a patient sample drawn on October 12th?
A. Yes, a new sample would not be needed
B. Yes, but only if the previous sample has no
alloantibodies
C. No, a new sample is needed because the 2-day
limit has expired
D. No, a new sample is needed for each testing
A
A. Yes, a new sample would not be needed
6
Q
- A type and screen was performed on a 32-year-old
woman, and the patient was typed as AB negative.
There are no AB-negative units in the blood bank.
What should be done?
A. Order AB-negative units from a blood supplier
B. Check inventory of A-, B-, and O-negative units
C. Ask the patient to make a preoperative
autologous donation
D. Nothing—the blood will probably not be used
A
B. Check inventory of A-, B-, and O-negative units
7
Q
- What ABO types may donate to any other
ABO type?
A. A negative, B negative, AB negative, O negative
B. O negative
C. AB negative
D. AB negative, A negative, B negative
A
B. O negative
8
Q
- What type(s) of red cells is (are) acceptable to
transfuse to an O-negative patient?
A. A negative, B negative, AB negative, or
O negative
B. O negative
C. AB negative
D. AB negative, A negative, B negative
A
B. O negative
9
Q
- A technologist removed 4 units of blood from the
blood bank refrigerator and placed them on the
counter. A clerk was waiting to take the units for
transfusion. As she checked the paperwork, she
noticed that one of the units was leaking onto the
counter. What should she do?
A. Issue the unit if the red cells appear normal
B. Reseal the unit
C. Discard the unit
D. Call the medical director and ask for an opinion
A
C. Discard the unit
10
Q
- A donor was found to contain anti-K using pilot
tubes from the collection procedure. How would
this affect the compatibility test?
A. The AHG major crossmatch would be positive
B. The IS (immediate spin) major crossmatch
would be positive
C. The recipient’s antibody screen would be positive
for anti-K
D. Compatibility testing would not be affected
A
D. Compatibility testing would not be affected
11
Q
- Which of the following is not a requirement for
the electronic crossmatch?
A. The computer system contains logic to prevent
assignment and release of ABO incompatible
blood
B. There are concordant results of at least two
determinations of the recipient’s ABO type on
record, one of which is from the current sample
C. Critical elements of the system have been
validated on site
D. There are concordant results of at least one
determination of the recipient’s ABO type on file
A
D. There are concordant results of at least one
determination of the recipient’s ABO type on file
12
Q
- A patient showed positive results with screening
cells and 4 donor units. The patient autocontrol
was negative. What is the most likely antibody?
A. Anti-H
B. Anti-S
C. Anti-Kpa
D. Anti-k
A
D. Anti-k
13
Q
- Screening cells and major crossmatch are positive
on IS only, and the autocontrol is negative.
Identify the problem.
A. Cold alloantibody
B. Cold autoantibody
C. Abnormal protein
D. Antibody mixture
A
A. Cold alloantibody
14
Q
- Six units are crossmatched. Five units are
compatible, one unit is incompatible, and the
recipient’s antibody screen is negative. Identify
the problem:
A. Patient may have an alloantibody to a
high-frequency antigen
B. Patient may have an abnormal protein
C. Donor unit may have a positive DAT
D. Donor may have a high-frequency antigen
A
C. Donor unit may have a positive DAT
15
Q
- An incompatible donor unit is found to have a
positive DAT. What should be done with the
donor unit?
A. Discard the unit
B. Antigen type the unit for high-frequency
antigens
C. Wash the donor cells and use the washed cells
for testing
D. Perform a panel on the incompatible unit
A
A. Discard the unit
