extra 6 Flashcards

1
Q

what do glucocorticoids stress response

A

decreases affinity of insulin response

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2
Q

what does somatostatin do

A

inc sympathetic acivity
during exersice or acute stress
ensures glucose supply to brain and active muscle

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3
Q

what increases glucose uptake by fat cells and resting skeletal muscle

A

insulin

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4
Q

insulin on fat breakdown

A

inhibit lypolysis

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5
Q

what is the source of glucose for the brain during a fast

A

protein

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6
Q

what is the primary energy resivoir

A

fat

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7
Q

what is the first energy source

A

glucose

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8
Q

how much energy is in fat

A

two months

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9
Q

what pancreatic hormones are released by exocytosis

A

endocrine

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10
Q

alpha cells colour

A

light yellow

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11
Q

beta cells colour

A

orange

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12
Q

d cells colour

A

purple

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13
Q

what does glucose absorption from digestive tract do to blood glucose

A

increases blood glucose

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14
Q

major control of insulin secretion

A

glucose control

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15
Q

what does insulin decrease

A

blood glucose, fatty acids, amino acids

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16
Q

can glucose enter the cell without insulin

A

no

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17
Q

down regulation vs affinity decreasing of insulin

A

down regulated by insulin
decreased affinity due to glucocorticoids and stress

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18
Q

what activates enzymes that catalyze synthesis of FA from glucose

A

insulin

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19
Q

what hormones are secreted when there is high amino acids

A

both insulin and glucagon

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20
Q

what is the glucagon receptor

A

Gprotein coupled transmembrane protein
CAMP is the second messenger system

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21
Q

what increses lypolysis

A

GH, epinephrine, cortisol

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22
Q

what is the functional unit of striated muscle

23
Q

what is the contractile element of muscle fibre

24
Q

what is myosin

A

the part of the muscle that actually moves. has the myosin head

25
what kind of tissue has one end plate per cell
skeletal muscle
26
low threshold motor neurons
a2
27
hight threshold motor neuron
a1
28
what neurotransmitter is released by motor neuron action potential
acetylcholine
29
where is acetylcholine released in skeletal muscle
in the motor endplate the space bw the nerve and muscle
30
what does ach binding to its receptor in skeletal muscle cause
channel to open and let in Na and k out depolarization happens fast na channels produce AP AP transmitted down t tubule causing ca release from SR
31
what increases the force of contraction
firing frequency
32
what type of fibres have large amounts of myoglobin, mitochondria, blood supply,
a2- type 1- slow twitch
33
which fibres are fatigue reistant, low work intensities, oxidative, marathon
slow twich fibres
34
what fibres are activates at hig work intensities, fast shortening velocities, and fatigue more easily
fast twitch
35
what are the two types of fast twitch
oxidatitive and glycolytic
36
what type number are fast twitch
type 2
37
elevation of camp, camp dependant kinases
inhibit myosin and actin cross bridging pharmacomechanical relaxation
38
what happens with increased intracellular calcium
contraction of mooth muscle
39
what is soley mediated by electromechanical coupling
skeletal and cardiac muscle contraction
40
what releases ca from SR
IP3 receptors
41
what ion do smooth muscles use to make AP
Ca
42
What connects unitary smooth muscle cells
gap junctions
43
what increases slow wave frequency
acetylcholine and parasypathetic via M3
44
what decreases slow wave frequency
adrenaline and symapthetic via B2
45
what does MLCK phosphorylate
myosin
46
what does myosin phosphorylation lead to
actin myosin cross bridging
47
what do intercalated discs contain
gap junctions in cardiac muscle
48
what does the small ca influx due to na depolarization in atrical and ventricular cells do
triggers large release of ca from sarcoplasmic reticulum resulting in contraction
49
what does the AP traveling through t tubule sysem activate in skeletal muscle
DHP which mechanically releases ca from SR
50
what does the AP traveling through t tubule sysem activate in cardiac muscle
oepns voltage gated ca channels that allow ca in wich induces ca release from SR
51
what receptors increase heart rate and what receptors slow it down
b1 m2
52
what does stretching the cardiac muscle do
produces optimal orientation of actin myosin allowing GREATER CONTRACTILE FORCE
53
sterlings law of the haert
more blood is more contractility and larger ejection fracion