extra 2 Flashcards
where are tropes found
in the anterior pituitary
hypophysis meaning
pituitary
what is prolactin inhibiting hormone also known as
dopamine
what is growth hormone inhibiting hormone also known as
somatostatin
where do
glycoprotein
POMC
GH and prolcatin hormones made
they are hormone 2 of the feedback loop
in the anterior pituitary
what do FSH and LH do
stimulate folicular development and secretion of estrogen and progesterone in the ovaries
stimulate spermatogenesis and androgen production in the testes
what cells does ACTH target
in the adrenal gland cortex
what does ACTH do
controls or modulates the secretion of adrenal cortical hormones
what are the adrenal cortical hormones
Aldosterone
cortisol
androgens
what are the additional roles of prolactin
fertility regulation and maintenance of immune system
what kind of hormones are GH
peptide
what kind of hormones is prolactin
peptide
GH and fat
increases fat breakdown and use of fatty acids
what does GH promote
hypertrophy and hyperplasia in tisssues
what entraps chondrocytes
calcification of extracellular matrix entraps and entomsthe chondrocytes
when do humans reach the end of their determinate growth
at 20 yrs
what are the major inputs of GH secretion
exercise and stress
decrease in blood glucose
dinural rhythm
what are the minor inputs of GH secretion
inc blood AA
dec FA
ghrelin
what does IGF1 promote
cell division
protein synthesis to decrease AA
inc in bone growth
what are the metabolic actions unrelated to growth for GH
fat breakdown
dec glucose uptake
inc glucose output by liver to inc blood glucose
what has actute metabolic effects- diabetogenic actions
GH
what stimulates long term growth effects
IGF1 from GH
what does arginine and leucine lead to
secretion of GH
what happens in the first two hours of sleep
secretion of GH
what happens to height in acromegaly
unchanged
what happens to height in gigantism
taller
what does turners syndome present as
short stature
XO
GH recommended at puberty
pituitary dwarfism
GH, GHRH, or IGF1 deficiency
larons disease
unresponsive GH receptors
cretinism
hypothyroidism
lack of thyroid hormones so lack of GH bc thyroid hormones are permissive for GH action
poor long bone growth
achondroplasia
gene defect for cartilage FGF receptor which impairs bone ossification
