extra Flashcards

1
Q

how is hormone availability controlled

A
  1. secretino
  2. activation
  3. bidnding of lipophilic hormones in plasma
  4. inactivation
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2
Q

is phosphorylatino for peptide or lipid hormones

A

peptide

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3
Q

when is signal amplification used

A

in CAMP second messenger systems

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4
Q

where are neurosecretory neuronal cell bodies

A

in hypothalamus (PVN and SO)

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5
Q

preprooxyphysin and preprovasopressin

A

the things produced from the large precursor by PVN and SO

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6
Q

what cuases vasocnonstriction in vascular smooth muscle to maintian blood pressure

A

vasopressin

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7
Q

secretion stimuli for ADH

A

hyperosmolarity
hypovolemia
low blood pressure in arteries

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8
Q

where are osmoeceptor neurons outside BBB

A

OVLT and SFO

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9
Q

WHERE are blood volume receptors for ADH

A

easily stretchable low pressure areas
large veins
heart atria

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10
Q

what does alcohol inhibit

A

ADH secretion

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11
Q

where do hormones enter circulatino into blood from the brain

A

hypothalamic- hypophyseal portal system

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12
Q

what do somatotropes produce

A

growth hormone

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13
Q

what do thyrotropes produce

A

TSH

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14
Q

what do corticotropes produce

A

ACTH

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15
Q

what do lactotropes procuce

A

prolactin

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16
Q

waht do gonadotropes produce

A

LH and FSH

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17
Q

three classes of homrones

A

amines
peptide
steroid

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18
Q

what part of the pituitary is hypothalic hypophysela portal system for

A

anteriro pituitary

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19
Q

where are peptide hormones produced

A

in rough ER

20
Q

where are catecholaminse produced

A

in cytosol

21
Q

where are thyroid hormones produced

A

in colloid

22
Q

wehre are steroid hormones produced

A

from choleterol stepwise in various compartments

23
Q

what hormones are stored in secretory granules

A

peptide

24
Q

where are catecholamines stored

A

in choromaffin granules

25
Q

where are thyroid hormones stored

A

in colloid

26
Q

where are lipid hormones stored

A

not stored but cholesterol is stored in lipid droplets

27
Q

how are catecholamines transported in the blodo

A

half bound to plasma proteins

28
Q

how are thyroid hormones transported in blood

A

mostly bound to plasma proteins

29
Q

are are steroid hormones transported in the blodo

A

mostly bound to plasma proteins

30
Q

posterior pituitary connection to hypothalamus

A

hypothalamic posterior pituitary stak

31
Q

hypophysiotropic hormones

A

from hypothalamus that inhibit anterior pituitary
PIH/ dopamine
GHIH

32
Q

what cells secrete releasing and inhibiting hormones from hypothalamsu

A

neurosecretory neurons in hypothalamus

33
Q

what does hormone 3 negative feedback onto

A

hormone 2 and hormone 1

34
Q

hormones of the adrenal cortex

A

cortisol
aldosterone
androgen

35
Q

what are the additional roles of proalctin

A

fertility regulation and maintenance of immune system

36
Q

GH and glucose and glycogen

A

dec glycogen synth
dec glucose use
inc blood glucose
inc glucose uptake by muscles
gluconeogenesis

37
Q

where is IGF-1 released from

A

the liver

38
Q

GH and blood fatty acid

A

increases it

39
Q

what has diabetogenic effects

A

GH

40
Q

what causes secretion of GH

A

excersize
stress
dinural rhythm- first two hours of deep sleep
inc blood AA- arginine and leucine
hypoglycemia
low blood FA
ghrelin

41
Q

GHRH, GH, IGF1 deficiency

A

pituitary dwarfism

42
Q

unresponsive GH receptors

A

larons dwarfism

43
Q

hypothyroidism bc thyroid permissive for GH

A

cretinism- poor long bone growth

44
Q

gene defect for FGF

A

achondroplasia- impaired bone ossificatin

45
Q

which hromones are catecholamines

A

only from adrenal medulla

46
Q

which hormones are steroid hormones

A

hormones from adrenal cortex and gonads